Detailed information NTG0845452

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V2189_RS09160
• Genome accession: NZ_CP143908
• Coordinates: 1915958..1918234 (+)
• Length: 758 a.a.
• NCBI ID: WP_003090432.1
• Uniprot ID: A0A0H2ZAW8
• Organism: Pseudomonas aeruginosa strain PA4_YH3_36.21_ST773_NDM1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1910958..1923234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V2189_RS09140 (V2189_09140)	-	1911150..1913375 (-)	2226	WP_003090437.1	NADP-dependent isocitrate dehydrogenase	-
V2189_RS09145 (V2189_09145)	icd	1913734..1914990 (+)	1257	WP_003090436.1	NADP-dependent isocitrate dehydrogenase	-
V2189_RS09150 (V2189_09150)	cspD	1915064..1915336 (-)	273	WP_003090435.1	cold shock domain-containing protein CspD	-
V2189_RS09155 (V2189_09155)	clpS	1915562..1915930 (+)	369	WP_003097649.1	ATP-dependent Clp protease adapter ClpS	-
V2189_RS09160 (V2189_09160)	clpC	1915958..1918234 (+)	2277	WP_003090432.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
V2189_RS09165 (V2189_09165)	infA	1918316..1918534 (-)	219	WP_002553999.1	translation initiation factor IF-1	-
V2189_RS09170 (V2189_09170)	-	1918639..1919346 (-)	708	WP_003097644.1	arginyltransferase	-
V2189_RS09175 (V2189_09175)	aat	1919401..1920081 (-)	681	WP_033939920.1	leucyl/phenylalanyl-tRNA--protein transferase	-
V2189_RS09180 (V2189_09180)	trxB	1920119..1921069 (-)	951	WP_034005901.1	thioredoxin-disulfide reductase	-

Sequence

Protein

• Length: 758 a.a.
• Molecular weight: 84010.68 Da
• Isoelectric Point: 5.8904

>NTDB_id=845452 V2189_RS09160 WP_003090432.1 1915958..1918234(+) (clpC) [Pseudomonas aeruginosa strain PA4_YH3_36.21_ST773_NDM1]
MLNRELEVTLNLAFKEARAKRHEFMTVEHLLLALLDNEAAATVLRACGANLDKLRRDLQEFIDSTTPLIPQHDDERETQP
TLGFQRVLQRAVFHVQSSGKREVTGANVLVAIFSEQESQAVFLLKQQSIARIDVVNYIAHGISKVPGHAEHPQDGEQDMQ
DEEGGESATSNHPLDAYASNLNELARQGRIDPLVGREHEVERVAQILARRRKNNPLLVGEAGVGKTAIAEGLAKRIVDGQ
VPDLLADSVVYSLDLGALLAGTKYRGDFEKRFKALLNELRKRPHAVLFIDEIHTIIGAGAASGGVMDASNLLKPVLSSGE
IRCIGSTTFQEFRGIFEKDRALARRFQKVDVTEPSVEDTYGILKGLKGRFEQHHHIEYSDEALRAAAELAARYINDRHMP
DKAIDVIDEAGAYQRLQPEEKRVKRIEVAQVEDIVAKIARIPPKHVTTSDKELLRNLERDLKLTVFGQDDAIESLSTAIK
LSRAGLKAPDKPVGSFLFAGPTGVGKTEVARQLAKALGVELVRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTEAITK
TPHCVLLLDEIEKAHPEVFNLLLQVMDHGTLTDNNGRKADFRNIILIMTTNAGAEVAARASIGFNQQDHTTDAMEVIKKS
FTPEFRNRLDTIIQFGRLSTETIKSVVDKFLTELQAQLEDKRVQLEVSDAARGWLAEKGYDVQMGARPMARLIQDKIKRP
LAEEILFGELAEHGGLVHVDLKGDELAFEFEITAAEPA

Nucleotide

• Length: 2277 bp

>NTDB_id=845452 V2189_RS09160 WP_003090432.1 1915958..1918234(+) (clpC) [Pseudomonas aeruginosa strain PA4_YH3_36.21_ST773_NDM1]
ATGTTGAATCGAGAGCTCGAAGTCACCCTCAATCTCGCCTTCAAGGAGGCGAGGGCCAAACGCCATGAATTCATGACGGT
TGAGCACCTGCTGCTGGCCTTGCTGGACAATGAGGCGGCGGCAACGGTATTGCGTGCGTGCGGTGCCAACCTGGACAAGC
TGCGGCGCGACCTGCAGGAATTCATCGATTCCACCACGCCGCTGATCCCGCAGCACGACGACGAGCGCGAAACCCAGCCG
ACGCTGGGCTTCCAGCGCGTCCTGCAGCGTGCGGTGTTCCACGTGCAGAGTTCCGGCAAGCGCGAAGTGACCGGGGCCAA
TGTCCTGGTGGCGATCTTCAGCGAACAGGAAAGCCAGGCGGTGTTCCTGCTCAAGCAGCAGAGCATCGCGCGTATCGATG
TGGTGAACTACATCGCCCACGGCATCTCCAAGGTGCCCGGGCATGCCGAACATCCGCAGGATGGGGAGCAGGATATGCAG
GATGAGGAAGGTGGCGAGTCGGCCACGTCCAACCATCCGCTGGACGCCTATGCCAGCAACCTCAACGAACTGGCTCGCCA
GGGGCGGATCGACCCGCTGGTGGGGCGTGAGCATGAAGTCGAGCGGGTGGCGCAGATCCTTGCCCGCCGGCGCAAGAACA
ACCCGCTGCTGGTAGGCGAGGCGGGGGTCGGCAAGACGGCCATCGCCGAAGGCCTGGCCAAGCGCATCGTCGATGGCCAG
GTGCCGGACCTGCTGGCCGACAGCGTGGTCTACTCCCTCGACCTGGGTGCCTTGCTCGCGGGTACCAAGTACCGCGGCGA
CTTCGAGAAGCGCTTCAAGGCCTTGCTCAACGAGTTGCGCAAGCGCCCGCACGCGGTGCTGTTCATCGACGAGATCCATA
CCATCATCGGCGCCGGTGCAGCATCCGGCGGGGTAATGGACGCCTCCAACCTGCTCAAGCCGGTTCTGTCCTCGGGCGAG
ATCCGCTGCATCGGCTCGACCACCTTCCAGGAGTTCCGCGGCATCTTCGAGAAGGACCGGGCCTTGGCGCGGCGCTTCCA
GAAGGTCGACGTGACCGAGCCGTCGGTGGAAGACACCTATGGCATCCTCAAGGGCCTCAAGGGGCGCTTCGAGCAGCATC
ACCACATCGAGTACAGCGACGAGGCGCTGCGCGCCGCGGCCGAGCTGGCGGCGCGCTACATCAACGACCGGCACATGCCG
GACAAGGCCATCGACGTCATCGACGAGGCGGGCGCCTACCAGCGCCTGCAGCCGGAAGAGAAGCGCGTGAAGCGCATCGA
GGTGGCGCAGGTCGAGGATATCGTGGCGAAGATCGCGCGGATCCCGCCGAAACACGTCACCACCTCGGACAAGGAGTTGC
TGCGCAACCTCGAACGCGACCTCAAGCTGACCGTGTTCGGCCAGGACGACGCCATCGAGTCGCTGTCCACCGCGATCAAG
CTGTCCCGGGCCGGGCTCAAGGCGCCGGACAAGCCGGTCGGCTCGTTCCTCTTCGCCGGTCCCACCGGCGTGGGCAAGAC
CGAAGTGGCGCGGCAGTTGGCGAAGGCCTTGGGCGTGGAACTGGTGCGCTTCGACATGTCCGAGTACATGGAGCGGCATA
CCGTGTCGCGGCTGATCGGTGCGCCTCCGGGCTACGTCGGCTTCGACCAGGGCGGCCTGCTCACCGAGGCGATCACCAAG
ACCCCGCACTGCGTGTTGCTGCTCGACGAGATCGAGAAGGCTCACCCGGAGGTCTTCAACCTGCTGCTGCAGGTGATGGA
CCACGGCACCCTGACCGACAACAACGGGCGCAAGGCGGACTTCCGCAACATCATCCTGATCATGACCACCAACGCCGGCG
CAGAAGTGGCGGCGCGCGCGTCGATCGGCTTCAACCAGCAGGATCACACCACCGATGCGATGGAAGTGATCAAGAAGAGC
TTCACCCCGGAGTTCCGCAACCGCCTGGATACCATCATCCAGTTCGGCCGCCTGAGCACCGAGACGATCAAGAGCGTGGT
CGACAAGTTCCTCACCGAGCTGCAGGCGCAGTTGGAGGACAAGCGCGTCCAGCTCGAGGTCAGCGATGCGGCGCGCGGCT
GGCTGGCGGAGAAGGGCTACGACGTGCAGATGGGTGCGCGACCGATGGCGCGGCTTATCCAGGACAAGATCAAGCGGCCG
TTGGCCGAGGAGATCCTGTTCGGCGAGCTGGCCGAGCATGGCGGCCTGGTGCATGTCGACCTGAAGGGCGACGAGCTGGC
CTTCGAGTTCGAGATCACGGCGGCGGAGCCCGCCTGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (216-328)

• AAA lid domain (AAA_lid_9) (355-458)

• AAA domain (Cdc48 subfamily) (AAA_2) (491-652)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (658-739)

3D structure

• AlphaFold DB: A0A0H2ZAW8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	38.956	100	0.423
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.667	96.57	0.402
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.247	100	0.389
clpC	Streptococcus mutans UA159	45.484	81.794	0.372
clpC	Lactococcus lactis subsp. cremoris KW2	44.586	82.85	0.369