Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/comEC   Type   Machinery gene
Locus tag   JMH49_RS10515 Genome accession   NZ_AP024270
Coordinates   1948390..1950423 (+) Length   677 a.a.
NCBI ID   WP_201351019.1    Uniprot ID   -
Organism   Thermus thermophilus strain HB5018     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1943390..1955423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMH49_RS10480 (TthHB5018_20780) - 1944168..1944632 (+) 465 WP_201351017.1 hypothetical protein -
  JMH49_RS10485 (TthHB5018_20790) pfkA 1944609..1945577 (-) 969 WP_011173968.1 6-phosphofructokinase -
  JMH49_RS10490 (TthHB5018_20800) rsmI 1945574..1946368 (-) 795 WP_201351018.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  JMH49_RS10495 (TthHB5018_20810) - 1946370..1946864 (-) 495 WP_011173970.1 hypothetical protein -
  JMH49_RS10500 (TthHB5018_20820) - 1946928..1947455 (-) 528 WP_011173971.1 inorganic diphosphatase -
  JMH49_RS14250 - 1947488..1948112 (+) 625 Protein_2056 YcxB family protein -
  JMH49_RS10510 (TthHB5018_20850) comEA 1948085..1948393 (+) 309 WP_024119555.1 helix-hairpin-helix domain-containing protein Machinery gene
  JMH49_RS10515 (TthHB5018_20860) comA/comEC 1948390..1950423 (+) 2034 WP_201351019.1 ComEC/Rec2 family competence protein Machinery gene
  JMH49_RS10520 (TthHB5018_20870) - 1950411..1951220 (-) 810 WP_011173975.1 ParB/RepB/Spo0J family partition protein -
  JMH49_RS10525 (TthHB5018_20880) soj 1951204..1951953 (-) 750 WP_201351020.1 chromosome-partitioning ATPase Soj -
  JMH49_RS10530 (TthHB5018_20890) rsmG 1951947..1952696 (-) 750 WP_024119551.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  JMH49_RS10535 (TthHB5018_20900) mnmG 1952696..1954489 (-) 1794 WP_201351021.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG -

Sequence

Protein


Download         Length: 677 a.a.        Molecular weight: 71947.02 Da        Isoelectric Point: 10.0614

>NTDB_id=84451 JMH49_RS10515 WP_201351019.1 1948390..1950423(+) (comA/comEC) [Thermus thermophilus strain HB5018]
MRPSWTWGVGLGAGALVAAWGLFAPWAFLGLGLLPFLRLPFALGFGLVLARALFFPLPEPPWGAAVEGVFAVRGGFTRAE
GHLLWVSHYPPLPDGRYRLRGRIAPPQGRTNPGGFDQRAWLLSRGAKGVLRAESAEPLGPLPDWREGFRERLGAGLSLEA
REVVEGLVLGDKGGLETAYPLFQRAGLAHLLALSGLHVGVLVGFAVLGLYPLGRWRYLLALALLPFYLLLAGPSPSLVRA
SLMAGLSLLGLFLGLGGAGVVQALGLALFLQLLLRPEALLGLGFQLSYLAVLGLALVLPALRLPPGPRGYLLGGVAASLA
VQAFLLPLLLHRFGFAPLLAPLANLLALPLVALLVPLGFLKLFLGALPAPLVEPLARGLLLLAGLAAQGPLLRWGEIAPP
GFALYYLGLLPLLFALHRRLPWRRALLLASLPALVGLLAAWPKPLDLWMLDVGQGDALLARMGGGEVLVDGGRAEKGEAV
VRALRALGVEALELLVATHPDADHYGGLFRVIEEVPVGLALLAPGFPEDHPLAQALRARGVPVVRAGAGTRLKVGQGEVR
VLWPEALSGDDNQDGLALLLDFGRGRALLLADLPREVEARLPVGEVEALKVSHHGSQSGTSEVLLERTRPRVALIGVGPN
PFGHPHPEVLERLERHGAEIRRTDQDGAVRVLFGYAW

Nucleotide


Download         Length: 2034 bp        

>NTDB_id=84451 JMH49_RS10515 WP_201351019.1 1948390..1950423(+) (comA/comEC) [Thermus thermophilus strain HB5018]
ATGAGGCCTTCTTGGACCTGGGGAGTGGGGCTTGGGGCGGGGGCTTTGGTGGCCGCCTGGGGGCTTTTCGCGCCTTGGGC
CTTCCTTGGGCTCGGCCTCCTTCCCTTCCTCCGCCTTCCCTTCGCCCTGGGCTTCGGCCTCGTCCTGGCCCGGGCCCTTT
TCTTCCCCTTGCCCGAGCCCCCGTGGGGCGCCGCCGTGGAGGGGGTCTTCGCCGTGAGGGGCGGGTTCACACGGGCGGAG
GGCCACCTCCTCTGGGTGAGCCACTATCCCCCTCTACCGGACGGCCGCTACCGCCTCCGGGGGCGCATCGCCCCGCCCCA
AGGCCGGACCAACCCCGGGGGGTTTGACCAACGGGCCTGGCTCCTGAGCCGGGGGGCCAAGGGGGTGCTCCGGGCCGAAA
GCGCCGAGCCCTTGGGGCCCCTGCCCGACTGGAGGGAGGGGTTCCGGGAACGCCTAGGGGCGGGCCTGAGCCTCGAGGCC
CGGGAGGTGGTGGAGGGCCTGGTCCTCGGGGACAAGGGGGGCTTAGAGACGGCCTACCCCCTCTTCCAGCGGGCGGGCCT
CGCCCACCTCCTGGCGCTCTCTGGCCTTCACGTGGGGGTGCTCGTGGGCTTCGCCGTCCTCGGCCTCTACCCCCTGGGGC
GGTGGCGCTACCTCCTGGCCCTCGCCCTCCTCCCCTTTTACCTCCTCCTCGCCGGGCCGAGCCCCTCCCTGGTGCGGGCG
AGCCTCATGGCGGGCCTGTCCCTCCTCGGCCTCTTCCTGGGCCTTGGGGGGGCCGGGGTGGTCCAGGCCCTGGGGCTCGC
CCTCTTCCTCCAGCTCCTCCTCCGCCCCGAGGCCCTCCTCGGCCTCGGGTTCCAGCTCTCCTACCTCGCGGTGCTGGGCC
TGGCCCTGGTCCTCCCGGCCCTGAGGCTTCCCCCGGGCCCCAGGGGCTATCTCCTCGGGGGCGTGGCCGCAAGCCTGGCC
GTCCAGGCCTTCCTCCTCCCCCTCCTCCTCCACCGCTTCGGCTTCGCCCCTCTCCTCGCCCCCCTCGCCAACCTCCTCGC
CCTCCCCCTGGTGGCCCTCCTCGTGCCCCTCGGCTTCCTCAAGCTCTTCCTCGGCGCCCTCCCCGCCCCCCTGGTGGAGC
CCCTCGCCCGGGGGCTCCTCCTCCTGGCGGGGCTTGCGGCCCAAGGGCCCCTCCTCCGCTGGGGGGAGATCGCCCCCCCA
GGCTTTGCCCTCTACTACCTGGGCCTTCTCCCCCTCCTTTTCGCCCTCCACCGCAGGCTTCCCTGGCGGCGCGCCCTCCT
CCTCGCCTCCCTGCCCGCCCTGGTGGGCCTCCTCGCCGCCTGGCCCAAGCCGCTGGACCTCTGGATGCTGGACGTGGGCC
AGGGGGACGCCCTCCTCGCCCGCATGGGGGGCGGGGAGGTCCTGGTGGACGGGGGACGGGCGGAGAAGGGGGAGGCGGTG
GTCCGGGCCCTCCGCGCCCTCGGGGTGGAGGCCCTGGAGCTTTTGGTGGCCACCCACCCCGACGCGGACCACTACGGGGG
GCTTTTCCGGGTGATAGAGGAGGTTCCCGTGGGCCTTGCCCTCCTCGCCCCCGGCTTCCCCGAGGACCACCCCCTGGCCC
AGGCCCTAAGGGCGCGGGGCGTCCCCGTGGTGCGGGCCGGGGCGGGAACCCGCCTTAAGGTGGGCCAGGGCGAGGTCCGG
GTGCTCTGGCCCGAGGCCCTCTCCGGGGACGACAACCAAGACGGCCTCGCCCTCCTCCTGGACTTCGGCCGGGGACGGGC
CCTCCTCCTCGCCGACCTGCCCCGGGAGGTGGAGGCCAGGCTTCCCGTGGGGGAGGTGGAGGCGCTCAAGGTGAGCCACC
ACGGCTCCCAGAGCGGCACCTCCGAGGTCCTCCTGGAAAGGACGAGGCCCCGGGTGGCCCTCATCGGGGTGGGGCCCAAC
CCCTTCGGCCACCCCCACCCCGAGGTCCTGGAGCGCCTTGAGCGCCACGGCGCGGAGATACGCCGCACCGACCAGGACGG
GGCGGTGCGCGTCCTCTTCGGCTACGCCTGGTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(451-635)

Competence protein (Competence)

(167-418)

Domain of unknown function (DUF4131) (DUF4131)

(93-136)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/comEC Thermus thermophilus HB27

99.852

100

0.999
  comEC Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

40.85

90.399

0.369

Multiple sequence alignment