Detailed information NTG0084431

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: JMH49_RS01325
• Genome accession: NZ_AP024270
• Coordinates: 238789..239793 (-)
• Length: 334 a.a.
• NCBI ID: WP_024118955.1
• Uniprot ID: -
• Organism: Thermus thermophilus strain HB5018
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 233789..244793

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMH49_RS01300 (TthHB5018_02490)	hisG	234683..235303 (+)	621	WP_201351102.1	ATP phosphoribosyltransferase	-
JMH49_RS01305 (TthHB5018_02500)	trmH	235300..235884 (+)	585	WP_143590344.1	tRNA (guanosine(18)-2'-O)-methyltransferase TrmH	-
JMH49_RS01310 (TthHB5018_02510)	-	235874..236827 (-)	954	WP_201351103.1	branched-chain amino acid transaminase	-
JMH49_RS01315 (TthHB5018_02520)	-	236814..237767 (-)	954	WP_201351104.1	hydrogen peroxide-inducible genes activator	-
JMH49_RS01320 (TthHB5018_02530)	-	237877..238785 (+)	909	WP_024118956.1	manganese catalase family protein	-
JMH49_RS01325 (TthHB5018_02540)	dprA	238789..239793 (-)	1005	WP_024118955.1	DNA-processing protein DprA	Machinery gene
JMH49_RS01330 (TthHB5018_02550)	era	239878..240783 (+)	906	WP_143590350.1	GTPase Era	-
JMH49_RS01335 (TthHB5018_02560)	-	240828..241715 (+)	888	WP_011174227.1	acyltransferase	-
JMH49_RS01345 (TthHB5018_02570)	-	241912..242886 (+)	975	WP_201351105.1	bifunctional oligoribonuclease/PAP phosphatase NrnA	-
JMH49_RS01350 (TthHB5018_02580)	-	242864..243412 (-)	549	WP_201351106.1	Uma2 family endonuclease	-
JMH49_RS01355 (TthHB5018_02590)	-	243422..244642 (-)	1221	WP_201351107.1	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 36217.10 Da
• Isoelectric Point: 6.8892

>NTDB_id=84431 JMH49_RS01325 WP_024118955.1 238789..239793(-) (dprA) [Thermus thermophilus strain HB5018]
MDPLALALLPGIGPKRLLEVLKAEDPLGFLRERFPEAWRHLPEAEAQAERERRRAEALGVRLLGLWEEGFPEGLKALPQP
PTHLYLKGELPPEREAVALVGTRRASPWALAFARRLARELAEAGLWVVSGLARGIDREAHLGALEAGGRTLGVLGSALDR
VYPPENRPLAQRMDLLSEFPFGTGPKPEFFPRRNRLIAGLCRAVVVVEAPLDSGALITARHALELGKEVLAVPGRPTDER
SLGANRLIQDGAYPVLSAEDVLSYLGMSARPKPLPGLSPEEEALYALLQEKKEALPEALAMALGIPPERVLSLLTLLELK
GLARALPGGRYGPG

Nucleotide

• Length: 1005 bp

>NTDB_id=84431 JMH49_RS01325 WP_024118955.1 238789..239793(-) (dprA) [Thermus thermophilus strain HB5018]
GTGGACCCCTTGGCCCTCGCCCTCCTTCCGGGCATCGGCCCCAAGCGGCTTCTGGAGGTCCTAAAGGCGGAGGACCCTCT
GGGCTTCCTGCGGGAGCGCTTCCCCGAGGCCTGGCGGCACCTCCCCGAGGCCGAGGCCCAGGCGGAAAGGGAGAGGCGGC
GCGCCGAGGCCCTAGGGGTGCGCCTCCTGGGCCTCTGGGAGGAGGGCTTCCCCGAGGGGCTGAAGGCGCTTCCCCAGCCG
CCCACCCACCTCTACCTGAAGGGGGAGCTTCCCCCGGAAAGGGAGGCGGTGGCCCTCGTGGGCACGCGCCGGGCCTCCCC
TTGGGCCCTGGCCTTTGCCAGGAGGCTCGCCCGGGAGCTGGCCGAGGCCGGGCTTTGGGTGGTCTCGGGCCTCGCCCGGG
GCATAGACCGGGAGGCCCACCTCGGGGCCCTCGAGGCCGGGGGGCGCACCCTGGGCGTCTTGGGAAGCGCCCTGGACCGG
GTCTACCCCCCGGAAAACCGCCCTTTGGCCCAACGGATGGACCTCCTCTCCGAGTTCCCCTTCGGCACCGGGCCCAAGCC
CGAGTTCTTTCCCCGGCGAAACCGCCTCATCGCCGGGCTTTGCCGGGCGGTGGTCGTGGTGGAGGCCCCTCTGGACTCCG
GGGCCCTCATCACCGCCCGCCACGCCCTGGAGCTCGGCAAGGAGGTGCTGGCCGTGCCCGGAAGGCCCACGGACGAGCGC
TCCCTGGGGGCGAACCGCCTCATCCAGGACGGGGCCTACCCGGTGCTCTCCGCCGAGGACGTCCTCTCCTACCTGGGAAT
GTCCGCAAGGCCCAAGCCCCTCCCGGGCCTCTCCCCGGAGGAGGAGGCCCTTTACGCCCTCCTGCAGGAAAAGAAGGAGG
CGCTCCCCGAGGCCCTGGCCATGGCCCTGGGGATCCCCCCGGAGCGGGTGCTCTCCCTCCTCACCCTTTTGGAGCTAAAG
GGCCTGGCCCGGGCCCTCCCGGGAGGGCGCTACGGGCCAGGCTAA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (269-329)

• DNA recombination-mediator protein A (DNA_processg_A) (56-255)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Thermus thermophilus HB27	99.102	100	0.991
dprA	Vibrio campbellii strain DS40M4	38.547	100	0.413
dprA	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	45.734	87.725	0.401
dprA	Vibrio cholerae strain A1552	37.535	100	0.401