Detailed information NTG0842080

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: P4A98_RS10395
• Genome accession: NZ_CP127126
• Coordinates: 2225788..2228013 (+)
• Length: 741 a.a.
• NCBI ID: WP_003138588.1
• Uniprot ID: A0A0H2ZCX3
• Organism: Pseudomonas aeruginosa PA14 strain MA3 isolate DTU_MIE
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2220788..2233013

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P4A98_RS10370 (P4A98_10370)	-	2221094..2221693 (-)	600	WP_016254241.1	PilZ domain-containing protein	-
P4A98_RS10375 (P4A98_10375)	-	2221796..2223046 (+)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
P4A98_RS10380 (P4A98_10380)	lolD	2223039..2223722 (+)	684	WP_003109474.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
P4A98_RS10385 (P4A98_10385)	-	2223792..2225036 (+)	1245	WP_003105198.1	lipoprotein-releasing ABC transporter permease subunit	-
P4A98_RS10390 (P4A98_10390)	-	2225124..2225657 (-)	534	WP_003091165.1	DUF2062 domain-containing protein	-
P4A98_RS10395 (P4A98_10395)	comA	2225788..2228013 (+)	2226	WP_003138588.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
P4A98_RS10400 (P4A98_10400)	exbB	2228086..2228721 (+)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
P4A98_RS10405 (P4A98_10405)	-	2228718..2229158 (+)	441	WP_003091161.1	biopolymer transporter ExbD	-
P4A98_RS10410 (P4A98_10410)	lpxK	2229158..2230156 (+)	999	WP_003091159.1	tetraacyldisaccharide 4'-kinase	-
P4A98_RS10415 (P4A98_10415)	-	2230194..2230379 (+)	186	WP_003091157.1	Trm112 family protein	-
P4A98_RS10420 (P4A98_10420)	kdsB	2230379..2231143 (+)	765	WP_003130694.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
P4A98_RS10425 (P4A98_10425)	-	2231143..2231607 (+)	465	WP_003138590.1	low molecular weight protein-tyrosine-phosphatase	-
P4A98_RS10430 (P4A98_10430)	murB	2231604..2232623 (+)	1020	WP_003119807.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79970.55 Da
• Isoelectric Point: 10.4652

>NTDB_id=842080 P4A98_RS10395 WP_003138588.1 2225788..2228013(+) (comA) [Pseudomonas aeruginosa PA14 strain MA3 isolate DTU_MIE]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GKVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHALLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPGWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
FLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=842080 P4A98_RS10395 WP_003138588.1 2225788..2228013(+) (comA) [Pseudomonas aeruginosa PA14 strain MA3 isolate DTU_MIE]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCAAGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCGGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGTGCTTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTATGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCGTTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGGGAGCATGCCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGGTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCGCAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGACCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
TTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A0H2ZCX3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.946	97.301	0.574
comA	Ralstonia pseudosolanacearum GMI1000	35.611	100	0.366