Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   VVB72_RS04645 Genome accession   NZ_CP142589
Coordinates   923876..924505 (+) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis subsp. lactis strain C20     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 918876..929505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VVB72_RS04620 (VVB72_04620) - 919163..920362 (+) 1200 WP_012897536.1 FtsW/RodA/SpoVE family cell cycle protein -
  VVB72_RS04625 (VVB72_04625) - 920393..921691 (+) 1299 WP_052230907.1 LCP family protein -
  VVB72_RS04630 (VVB72_04630) rpsN 921789..922058 (+) 270 WP_010905608.1 30S ribosomal protein S14 -
  VVB72_RS04635 (VVB72_04635) liaF 922224..922853 (+) 630 WP_039115115.1 cell wall-active antibiotics response protein LiaF -
  VVB72_RS04640 (VVB72_04640) - 922850..923848 (+) 999 WP_039115117.1 sensor histidine kinase -
  VVB72_RS04645 (VVB72_04645) vraR 923876..924505 (+) 630 WP_003131402.1 LuxR C-terminal-related transcriptional regulator Regulator
  VVB72_RS04650 (VVB72_04650) - 924576..925382 (+) 807 WP_270097350.1 Cof-type HAD-IIB family hydrolase -
  VVB72_RS04655 (VVB72_04655) - 925484..926074 (+) 591 WP_012897543.1 peptidylprolyl isomerase -
  VVB72_RS04660 (VVB72_04660) - 926076..926507 (+) 432 WP_039115127.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  VVB72_RS04665 (VVB72_04665) - 926504..927109 (+) 606 WP_012897545.1 TVP38/TMEM64 family protein -
  VVB72_RS04670 (VVB72_04670) - 927331..928575 (+) 1245 WP_015426198.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=841208 VVB72_RS04645 WP_003131402.1 923876..924505(+) (vraR) [Lactococcus lactis subsp. lactis strain C20]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=841208 VVB72_RS04645 WP_003131402.1 923876..924505(+) (vraR) [Lactococcus lactis subsp. lactis strain C20]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGATTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACGCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACGAGTTTTATTGATGACGAAAAAGTTTTTCCAGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATCGCATCTGCGATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGATGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416