Detailed information NTG0841135

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VOS73_RS08735
• Genome accession: NZ_CP142398
• Coordinates: 1839843..1842119 (+)
• Length: 758 a.a.
• NCBI ID: WP_000934036.1
• Uniprot ID: -
• Organism: Escherichia coli strain SX4
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1834843..1847119

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VOS73_RS08710 (VOS73_08735)	macA	1835814..1836929 (+)	1116	WP_000746460.1	macrolide transporter subunit MacA	-
VOS73_RS08715 (VOS73_08740)	macB	1836926..1838872 (+)	1947	WP_000188136.1	macrolide ABC transporter ATP-binding protein/permease MacB	-
VOS73_RS08720 (VOS73_08745)	cspD	1838945..1839169 (-)	225	WP_000410785.1	cold shock-like protein CspD	-
VOS73_RS08725 (VOS73_08750)	yljB	1839319..1839393 (+)	75	WP_001406719.1	protein YljB	-
VOS73_RS08730 (VOS73_08755)	clpS	1839492..1839812 (+)	321	WP_000520781.1	ATP-dependent Clp protease adapter ClpS	-
VOS73_RS08735 (VOS73_08760)	clpC	1839843..1842119 (+)	2277	WP_000934036.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
VOS73_RS08745 (VOS73_08770)	infA	1842744..1842962 (-)	219	WP_001040187.1	translation initiation factor IF-1	-
VOS73_RS08750 (VOS73_08775)	aat	1843246..1843950 (-)	705	WP_001241678.1	leucyl/phenylalanyl-tRNA--protein transferase	-
VOS73_RS08755 (VOS73_08780)	cydC	1843992..1845713 (-)	1722	WP_061092629.1	heme ABC transporter ATP-binding protein/permease CydC	-

Sequence

Protein

• Length: 758 a.a.
• Molecular weight: 84192.90 Da
• Isoelectric Point: 6.2512

>NTDB_id=841135 VOS73_RS08735 WP_000934036.1 1839843..1842119(+) (clpC) [Escherichia coli strain SX4]
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQP
TLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVM
ADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIG
STTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAID
VIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAG
LGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAV
LLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEF
RNRLDNIIWFDHLSSDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANEL
LFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH

Nucleotide

• Length: 2277 bp

>NTDB_id=841135 VOS73_RS08735 WP_000934036.1 1839843..1842119(+) (clpC) [Escherichia coli strain SX4]
ATGCTCAATCAAGAACTGGAACTCAGTTTAAATATGGCTTTCGCCAGAGCGCGCGAGCACCGTCATGAGTTTATGACCGT
CGAGCACTTGTTACTGGCGCTGCTCAGTAACCCATCTGCCCGGGAGGCGCTGGAAGCGTGTTCTGTGGATTTGGTTGCGC
TCCGTCAGGAACTGGAAGCCTTTATTGAACAAACCACACCCGTTCTGCCTGCCAGTGAAGAGGAGCGCGACACACAGCCG
ACGCTGAGTTTTCAGCGTGTACTGCAACGTGCGGTCTTCCATGTCCAGTCCTCCGGTCGCAATGAGGTTACCGGTGCAAA
CGTTTTGGTCGCTATCTTTAGCGAACAGGAGTCGCAGGCGGCATATCTGTTGCGTAAACATGAAGTCAGCCGTCTCGATG
TGGTGAACTTTATCTCTCATGGCACGCGTAAAGACGAGCCGACACAGTCTTCTGATCCTGGCAGCCAGCCAAACAGCGAA
GAACAAGCTGGTGGGGAGGAACGTATGGAGAATTTCACGACGAACCTGAATCAGCTTGCGCGAGTGGGCGGAATCGACCC
ACTGATTGGTCGTGAGAAGGAGCTGGAGCGTGCTATTCAGGTTCTCTGCCGTCGCCGTAAAAACAACCCGCTGCTGGTGG
GGGAGTCTGGTGTCGGTAAAACCGCGATTGCGGAAGGTCTTGCCTGGCGAATTGTTCAGGGCGATGTGCCGGAAGTGATG
GCTGACTGTACGATTTACTCTCTCGATATCGGTTCTCTGTTAGCGGGCACAAAATATCGCGGCGACTTTGAAAAACGTTT
TAAAGCGTTGCTCAAGCAGCTGGAGCAGGACACTAACAGCATCCTGTTTATTGATGAGATCCACACCATTATCGGTGCGG
GTGCAGCGTCTGGTGGCCAGGTCGATGCGGCTAACCTGATCAAACCGCTGCTCTCCAGCGGTAAAATTCGCGTAATTGGT
TCGACAACCTATCAGGAGTTCAGCAACATTTTCGAGAAAGACCGTGCTCTGGCGCGTCGCTTCCAGAAAATTGATATTAC
TGAACCGTCGATCGAAGAAACTGTTCAAATCATCAATGGCCTGAAACCGAAGTATGAAGCGCACCACGACGTGCGTTATA
CCGCAAAAGCGGTGCGTGCGGCGGTAGAGTTGGCGGTGAAATACATTAACGATCGTCATCTGCCGGATAAAGCGATTGAT
GTTATCGACGAAGCGGGCGCTCGCGCGCGTCTGATGCCGGTCAGCAAACGCAAGAAAACCGTTAATGTGGCGGATATTGA
GTCCGTGGTGGCCCGTATTGCACGCATTCCAGAGAAGAGTGTTTCTCAGAGTGACCGCGATACCCTGAAAAACCTCGGCG
ATCGCCTGAAAATGCTGGTCTTCGGTCAGGATAAAGCCATTGAGGCGCTGACTGAAGCCATTAAGATGGCGCGTGCAGGT
TTAGGTCACGAACATAAACCGGTCGGTTCGTTCCTGTTTGCCGGCCCTACCGGGGTCGGGAAAACAGAGGTGACGGTACA
GCTTTCGAAAGCTTTGGGCATTGAGCTTCTGCGCTTTGATATGTCCGAGTATATGGAACGCCATACCGTCAGCCGTCTGA
TTGGTGCACCTCCGGGATACGTTGGTTTTGATCAGGGCGGTTTGCTGACTGATGCGGTCATCAAGCATCCACATGCGGTG
CTGCTGCTGGACGAAATCGAGAAAGCGCACCCGGACGTGTTCAATATTCTGTTGCAGGTGATGGACAACGGTACGCTGAC
CGATAACAACGGACGTAAAGCGGACTTCCGTAACGTGGTATTGGTGATGACCACCAACGCTGGGGTACGAGAAACTGAGC
GTAAATCGATTGGTCTTATCCACCAGGACAACAGTACCGATGCGATGGAAGAGATCAAGAAGATCTTTACGCCGGAGTTT
CGTAACCGTCTCGACAACATTATCTGGTTCGATCATCTCTCCTCCGACGTGATCCATCAGGTAGTGGATAAATTCATCGT
CGAGTTGCAGGTTCAGCTGGATCAGAAAGGTGTTTCTCTGGAAGTGAGCCAGGAAGCGCGTAACTGGCTGGCCGAGAAAG
GTTACGACCGGGCAATGGGCGCACGTCCGATGGCGCGTGTCATCCAGGACAACCTGAAAAAACCGCTCGCCAACGAACTG
TTGTTTGGTTCGCTGGTGGACGGCGGTCAGGTGACGGTTGCGCTGGATAAAGAGAAAAATGAGCTGACTTATGGATTCCA
GAGTGCACAAAAGCACAAGGCGGAAGCAGCGCATTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-733)

• AAA domain (Cdc48 subfamily) (AAA_2) (486-647)

• AAA lid domain (AAA_lid_9) (350-452)

• ATPase family associated with various cellular activities (AAA) (AAA) (211-342)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	38.868	100	0.408
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.346	96.042	0.397
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	35.583	100	0.383
clpC	Streptococcus thermophilus LMD-9	42.37	89.05	0.377
clpC	Streptococcus thermophilus LMG 18311	42.222	89.05	0.376
clpC	Streptococcus mutans UA159	39.407	93.404	0.368
clpC	Streptococcus pneumoniae TIGR4	42.59	84.565	0.36
clpC	Streptococcus pneumoniae Rx1	42.59	84.565	0.36
clpC	Streptococcus pneumoniae D39	42.59	84.565	0.36