Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   VR625_RS14550 Genome accession   NZ_CP142147
Coordinates   3256378..3257502 (+) Length   374 a.a.
NCBI ID   WP_073874337.1    Uniprot ID   A0A5N5ESF5
Organism   Streptomyces sp. DSS69     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3251378..3262502
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VR625_RS14535 - 3251859..3252701 (+) 843 WP_109165029.1 hypothetical protein -
  VR625_RS14540 - 3252797..3254728 (-) 1932 WP_345982433.1 hypothetical protein -
  VR625_RS14545 radA/sms 3254875..3256296 (+) 1422 WP_109165027.1 DNA repair protein RadA Machinery gene
  VR625_RS14550 disA 3256378..3257502 (+) 1125 WP_073874337.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  VR625_RS14555 - 3257752..3258414 (+) 663 WP_345982434.1 zinc ribbon domain-containing protein -
  VR625_RS14560 - 3258430..3259182 (-) 753 WP_337192446.1 hypothetical protein -
  VR625_RS14565 - 3259508..3260419 (+) 912 WP_345982435.1 A/G-specific adenine glycosylase -
  VR625_RS14570 - 3260575..3261354 (+) 780 WP_345982436.1 SigE family RNA polymerase sigma factor -
  VR625_RS14575 - 3261462..3262115 (+) 654 WP_109165022.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40378.33 Da        Isoelectric Point: 5.0230

>NTDB_id=839948 VR625_RS14550 WP_073874337.1 3256378..3257502(+) (disA) [Streptomyces sp. DSS69]
MAANDRATAPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDMTKILRAGVQLVPDASIHTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=839948 VR625_RS14550 WP_073874337.1 3256378..3257502(+) (disA) [Streptomyces sp. DSS69]
GTGGCAGCCAACGACCGGGCGACAGCGCCCGGAAAGTCCGGCCAAGGCACCGGTAACGAGGCGCTGATGCGCGCCTCGCT
GAGCGCGGTCGCGCCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGGGGCAACACCGGGGGGCTGATCGTCC
TGGGCATGGACAAGACCGTCGAATCGATGTGTACCGGCGGGTTCGTGCTGGACGTGGAGTTCACCGCGACCCGCCTGCGC
GAGCTGTGCAAACTCGACGGGGCGCTGATCCTCGACAAGGACATGACCAAGATCCTGCGGGCCGGTGTGCAGCTGGTCCC
GGACGCCTCGATCCACACGGAGGAGACGGGGACCCGGCACCGTACGGCGGACCGGGTCTCCAAGGCGTGCGGCTTCCCCG
TCGTCTCGGTCTCCCAGTCCATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGGCGGGTCCTGGAGGAGTCCTCCGCG
ATCCTGTCCCGGGCCAACCAGGCGCTCGCCACGCTGGAGCGGTACAAGCTCCGCCTGGACGAGGTGGCCGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTCACGGCGGTGGCGCAGCGGCTGGAGATGGTGCGGCGGATCG
CGACGGAGATCGCGGAGTACGTGGTGGAGCTCGGCACCGACGGACGGCTCCTCTCGCTCCAGCTGGACGAGCTGATCGCG
GGCGTGGAGCCGGAGCGGGAGCTGGTGGTCCGCGACTATGTGCCCGAGCCGACGGCGAAACGATCGCGCACGGTGGCGGA
GGCGCTGACGGAGCTGGACGCGCTGAGCCACACGGAGCTGCTGGAGCTGCCGGTGGTGGCGCGGGCGCTGGGGTACAGCG
GCTCGCCGGAGACGCTGGACTCGGCGGTCTCGCCGCGGGGCTTCCGGCTGCTGGCGAAGGTGCCGAGGCTGCCGGGGGCG
ATCATCGAACGGCTGGTCGAGCACTTCGGGGGGCTCCAGAAGCTGCTGGCGGCGAGCGTGGACGACCTCCAGACCGTGGA
CGGCGTCGGGGAGGCGCGGGCCCGGAGCGTGCGGGAGGGGCTCTCGCGGCTGGCGGAGTCGTCGATCCTGGAACGGTACG
TCTGA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5N5ESF5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.152

96.524

0.436