Detailed information NTG0839305

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QPL68_RS13215
• Genome accession: NZ_CP126629
• Coordinates: 2716342..2717385 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 35-42
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2711342..2722385

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QPL68_RS13185 (QPL68_13185)	-	2712131..2712241 (+)	111	WP_001790257.1	hypothetical protein	-
QPL68_RS13190 (QPL68_13190)	-	2712270..2712683 (+)	414	WP_141060381.1	hypothetical protein	-
QPL68_RS13195 (QPL68_13195)	-	2712872..2713858 (-)	987	WP_000999712.1	aromatic acid exporter family protein	-
QPL68_RS13200 (QPL68_13200)	map	2714268..2715026 (+)	759	WP_063651082.1	type I methionyl aminopeptidase	-
QPL68_RS13205 (QPL68_13205)	-	2715243..2715629 (+)	387	WP_001110174.1	hypothetical protein	-
QPL68_RS13210 (QPL68_13210)	liaF	2715644..2716345 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QPL68_RS13215 (QPL68_13215)	vraS	2716342..2717385 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QPL68_RS13220 (QPL68_13220)	vraR	2717375..2718004 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
QPL68_RS13225 (QPL68_13225)	-	2718117..2719334 (-)	1218	WP_063651080.1	YihY/virulence factor BrkB family protein	-
QPL68_RS13230 (QPL68_13230)	-	2719612..2719887 (-)	276	WP_063651078.1	YtxH domain-containing protein	-
QPL68_RS13235 (QPL68_13235)	-	2719894..2720358 (-)	465	WP_063651075.1	low molecular weight protein-tyrosine-phosphatase	-
QPL68_RS13240 (QPL68_13240)	-	2720505..2720705 (+)	201	WP_000180460.1	DUF1128 family protein	-
QPL68_RS13245 (QPL68_13245)	-	2720708..2721964 (+)	1257	WP_217151847.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=839305 QPL68_RS13215 WP_001017131.1 2716342..2717385(+) (vraS) [Staphylococcus aureus strain 35-42]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=839305 QPL68_RS13215 WP_001017131.1 2716342..2717385(+) (vraS) [Staphylococcus aureus strain 35-42]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTACTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTGCAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1