Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   VJ737_RS32855 Genome accession   NZ_CP141909
Coordinates   7239228..7239869 (+) Length   213 a.a.
NCBI ID   WP_184599735.1    Uniprot ID   A0A7W4ZZK8
Organism   Streptomyces sp. CGMCC 4.1772     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7234228..7244869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VJ737_RS32835 (VJ737_32835) - 7235032..7235760 (-) 729 WP_184599731.1 transglycosylase SLT domain-containing protein -
  VJ737_RS32840 (VJ737_32840) - 7236040..7237158 (-) 1119 WP_184599732.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  VJ737_RS32845 (VJ737_32845) - 7237155..7237853 (-) 699 WP_184599733.1 SDR family oxidoreductase -
  VJ737_RS32850 (VJ737_32850) - 7238090..7239235 (+) 1146 WP_184599734.1 GAF domain-containing sensor histidine kinase -
  VJ737_RS32855 (VJ737_32855) vraR 7239228..7239869 (+) 642 WP_184599735.1 response regulator transcription factor Regulator
  VJ737_RS32860 (VJ737_32860) - 7240026..7240268 (+) 243 WP_114251215.1 chaplin -
  VJ737_RS32865 (VJ737_32865) - 7240456..7241244 (-) 789 WP_184599736.1 hypothetical protein -
  VJ737_RS32870 (VJ737_32870) - 7241406..7242203 (+) 798 WP_184599737.1 ABC transporter ATP-binding protein -
  VJ737_RS32875 (VJ737_32875) - 7242301..7242732 (+) 432 WP_184599738.1 NfeD family protein -
  VJ737_RS32880 (VJ737_32880) - 7242864..7243823 (+) 960 WP_184599739.1 SPFH domain-containing protein -
  VJ737_RS32885 (VJ737_32885) - 7243882..7244388 (-) 507 WP_184599740.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22967.23 Da        Isoelectric Point: 5.1434

>NTDB_id=838728 VJ737_RS32855 WP_184599735.1 7239228..7239869(+) (vraR) [Streptomyces sp. CGMCC 4.1772]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVDRAEELKPDVILMDVKMPGMDGVDALRRLRELDNPAR
VLVVTSFTEQRTVVPVLRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANSGPGRAGSLTDRERQVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLSDRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=838728 VJ737_RS32855 WP_184599735.1 7239228..7239869(+) (vraR) [Streptomyces sp. CGMCC 4.1772]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAGGTCGTCCGCCGGGGCCTGCGCACGTTCCTCGAGGTGCA
GGACGACATCGAGGTCGTCGGCGAGGCCGCGGACGGCGCCGAAGGAGTCGACCGTGCGGAGGAGTTGAAGCCCGACGTCA
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGTGTCGACGCCCTGCGCAGACTCCGCGAACTCGACAACCCCGCGCGC
GTGCTGGTCGTCACCAGCTTCACCGAGCAGCGCACGGTGGTGCCGGTCCTGCGCGCGGGCGCCGCCGGATACGTCTACAA
GGACGTCGACCCCGACGCCCTCGCCGGAGCCATCCGCTCCGTCCACGCCGGGCACATCCTCCTCCAGCCGGAGGTCGCCG
GTGCCCTGCTGTCCCAGGAGGAGGCCAACTCGGGGCCGGGAAGGGCCGGCTCGCTCACCGACCGGGAGCGCCAGGTACTC
GGCCTGATCGCGGACGGCCGCTCCAACCGGGAGATCGCCCGCGCGCTCGTCCTCTCCGAGAAGACCGTCAAGACCCACGT
CTCGAACATCCTGATGAAGCTCGACCTGTCCGACCGAACCCAGGCCGCCCTGTGGGCCGTTCGCCATGGCGTGACCGGCT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7W4ZZK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.226

99.531

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

36.652

100

0.38