Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | QMK35_RS09500 | Genome accession | NZ_CP126540 |
| Coordinates | 1976563..1977126 (-) | Length | 187 a.a. |
| NCBI ID | WP_107384866.1 | Uniprot ID | - |
| Organism | Staphylococcus cohnii strain SDAQ-1 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1935761..1976191 | 1976563..1977126 | flank | 372 |
Gene organization within MGE regions
Location: 1935761..1977126
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMK35_RS09220 (QMK35_09220) | - | 1935761..1936699 (-) | 939 | WP_285159479.1 | hypothetical protein | - |
| QMK35_RS09225 (QMK35_09225) | - | 1936853..1938271 (-) | 1419 | WP_285159480.1 | N-acetylmuramoyl-L-alanine amidase | - |
| QMK35_RS09230 (QMK35_09230) | - | 1938243..1938716 (-) | 474 | WP_285159481.1 | phage holin | - |
| QMK35_RS09235 (QMK35_09235) | - | 1938832..1939227 (-) | 396 | WP_285159483.1 | hypothetical protein | - |
| QMK35_RS09240 (QMK35_09240) | - | 1939211..1939651 (-) | 441 | WP_285159484.1 | hypothetical protein | - |
| QMK35_RS09245 (QMK35_09245) | - | 1939689..1939838 (-) | 150 | WP_285159485.1 | hypothetical protein | - |
| QMK35_RS09250 (QMK35_09250) | - | 1939831..1942233 (-) | 2403 | WP_285159486.1 | phage tail spike protein | - |
| QMK35_RS09255 (QMK35_09255) | - | 1942287..1944434 (-) | 2148 | WP_285159553.1 | hypothetical protein | - |
| QMK35_RS09260 (QMK35_09260) | - | 1944443..1945270 (-) | 828 | WP_285159554.1 | phage tail domain-containing protein | - |
| QMK35_RS09265 (QMK35_09265) | - | 1945286..1951264 (-) | 5979 | WP_285159555.1 | peptidoglycan DD-metalloendopeptidase family protein | - |
| QMK35_RS09270 (QMK35_09270) | gpG | 1951463..1951999 (-) | 537 | WP_107504739.1 | phage tail assembly chaperone G | - |
| QMK35_RS09275 (QMK35_09275) | - | 1952075..1952674 (-) | 600 | WP_285159556.1 | major tail protein | - |
| QMK35_RS09280 (QMK35_09280) | - | 1952678..1953091 (-) | 414 | WP_285159492.1 | hypothetical protein | - |
| QMK35_RS09285 (QMK35_09285) | - | 1953084..1953503 (-) | 420 | WP_107504735.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| QMK35_RS09290 (QMK35_09290) | - | 1953500..1953823 (-) | 324 | WP_285159493.1 | phage head closure protein | - |
| QMK35_RS09295 (QMK35_09295) | - | 1953793..1954122 (-) | 330 | WP_285159557.1 | head-tail connector protein | - |
| QMK35_RS09300 (QMK35_09300) | - | 1954132..1954299 (-) | 168 | WP_285159558.1 | hypothetical protein | - |
| QMK35_RS09305 (QMK35_09305) | - | 1954314..1955642 (-) | 1329 | WP_285159559.1 | phage major capsid protein | - |
| QMK35_RS09310 (QMK35_09310) | - | 1955693..1956250 (-) | 558 | WP_285159560.1 | HK97 family phage prohead protease | - |
| QMK35_RS09315 (QMK35_09315) | - | 1956237..1957475 (-) | 1239 | WP_285159561.1 | phage portal protein | - |
| QMK35_RS09320 (QMK35_09320) | - | 1957475..1957651 (-) | 177 | WP_285159499.1 | hypothetical protein | - |
| QMK35_RS09325 (QMK35_09325) | - | 1957665..1959413 (-) | 1749 | WP_285159562.1 | terminase large subunit | - |
| QMK35_RS09330 (QMK35_09330) | - | 1959406..1959876 (-) | 471 | WP_285159563.1 | phage terminase small subunit P27 family | - |
| QMK35_RS09335 (QMK35_09335) | - | 1960001..1960372 (-) | 372 | WP_285159503.1 | HNH endonuclease | - |
| QMK35_RS09340 (QMK35_09340) | - | 1961045..1961458 (-) | 414 | WP_210139481.1 | hypothetical protein | - |
| QMK35_RS09345 (QMK35_09345) | - | 1961472..1961780 (-) | 309 | WP_285159564.1 | hypothetical protein | - |
| QMK35_RS09350 (QMK35_09350) | - | 1961789..1962139 (-) | 351 | WP_285159565.1 | hypothetical protein | - |
| QMK35_RS09355 (QMK35_09355) | - | 1962136..1962267 (-) | 132 | WP_285159566.1 | transcriptional regulator | - |
| QMK35_RS09360 (QMK35_09360) | - | 1962446..1962721 (-) | 276 | WP_349017140.1 | DUF1381 domain-containing protein | - |
| QMK35_RS09365 (QMK35_09365) | - | 1962767..1963078 (-) | 312 | WP_285159568.1 | MazG-like family protein | - |
| QMK35_RS09370 (QMK35_09370) | - | 1963071..1963289 (-) | 219 | WP_046208763.1 | hypothetical protein | - |
| QMK35_RS09375 (QMK35_09375) | - | 1963291..1963500 (-) | 210 | WP_285159569.1 | hypothetical protein | - |
| QMK35_RS09380 (QMK35_09380) | - | 1963502..1963777 (-) | 276 | WP_285159570.1 | hypothetical protein | - |
| QMK35_RS09385 (QMK35_09385) | - | 1963977..1964282 (-) | 306 | WP_285159513.1 | DUF1140 family protein | - |
| QMK35_RS09390 (QMK35_09390) | - | 1964283..1964975 (-) | 693 | WP_285159571.1 | DUF3310 domain-containing protein | - |
| QMK35_RS09395 (QMK35_09395) | - | 1964976..1965194 (-) | 219 | WP_285159572.1 | hypothetical protein | - |
| QMK35_RS09400 (QMK35_09400) | - | 1965206..1965607 (-) | 402 | WP_285159573.1 | hypothetical protein | - |
| QMK35_RS09405 (QMK35_09405) | - | 1965609..1965797 (-) | 189 | WP_107504996.1 | hypothetical protein | - |
| QMK35_RS09410 (QMK35_09410) | - | 1965790..1966110 (-) | 321 | WP_285159574.1 | VRR-NUC domain-containing protein | - |
| QMK35_RS09415 (QMK35_09415) | - | 1966401..1968701 (-) | 2301 | WP_285159575.1 | phage/plasmid primase, P4 family | - |
| QMK35_RS09420 (QMK35_09420) | - | 1968722..1969222 (-) | 501 | WP_285159576.1 | DUF669 domain-containing protein | - |
| QMK35_RS09425 (QMK35_09425) | - | 1969225..1969923 (-) | 699 | WP_285159577.1 | hypothetical protein | - |
| QMK35_RS09430 (QMK35_09430) | - | 1969930..1971273 (-) | 1344 | WP_285159578.1 | DEAD/DEAH box helicase | - |
| QMK35_RS09435 (QMK35_09435) | - | 1971257..1971961 (-) | 705 | WP_285159579.1 | AAA family ATPase | - |
| QMK35_RS09440 (QMK35_09440) | - | 1971951..1972175 (-) | 225 | WP_210139088.1 | DUF2483 family protein | - |
| QMK35_RS09445 (QMK35_09445) | - | 1972172..1972435 (-) | 264 | WP_285159580.1 | DUF1108 family protein | - |
| QMK35_RS09450 (QMK35_09450) | - | 1972502..1972678 (-) | 177 | WP_204174229.1 | hypothetical protein | - |
| QMK35_RS09455 (QMK35_09455) | - | 1972680..1972886 (-) | 207 | WP_285159581.1 | hypothetical protein | - |
| QMK35_RS09460 (QMK35_09460) | - | 1972899..1973108 (-) | 210 | WP_285159582.1 | hypothetical protein | - |
| QMK35_RS09465 (QMK35_09465) | - | 1973136..1973366 (-) | 231 | WP_210129027.1 | helix-turn-helix domain-containing protein | - |
| QMK35_RS09470 (QMK35_09470) | - | 1973531..1973866 (+) | 336 | WP_285159583.1 | helix-turn-helix domain-containing protein | - |
| QMK35_RS09475 (QMK35_09475) | - | 1973878..1974342 (+) | 465 | WP_285159584.1 | ImmA/IrrE family metallo-endopeptidase | - |
| QMK35_RS09480 (QMK35_09480) | - | 1974430..1975080 (+) | 651 | WP_285159585.1 | DUF4352 domain-containing protein | - |
| QMK35_RS09485 (QMK35_09485) | - | 1975142..1976191 (+) | 1050 | WP_285159586.1 | site-specific integrase | - |
| QMK35_RS09500 (QMK35_09500) | comK/comK1 | 1976563..1977126 (-) | 564 | WP_107384866.1 | competence protein ComK | Regulator |
Sequence
Protein
Download Length: 187 a.a. Molecular weight: 22059.33 Da Isoelectric Point: 9.5680
>NTDB_id=838685 QMK35_RS09500 WP_107384866.1 1976563..1977126(-) (comK/comK1) [Staphylococcus cohnii strain SDAQ-1]
MIQPYIIKKGDMTLQPCHLPVGQYEGTRVLRYKEDESTIKERTHKIIDRSCRFYGSSYVFKKEDTIRITGISSKPPILFT
PLFPTYFFPTHSDRKTQNTWINIHYVQSIRSLKDKKCRVNFVDNQSIVVNISAHSMQHQYLNGIYYYYMMDRAARVATFD
PESPIDYTKPQLNIYEALAKYSLFESK
MIQPYIIKKGDMTLQPCHLPVGQYEGTRVLRYKEDESTIKERTHKIIDRSCRFYGSSYVFKKEDTIRITGISSKPPILFT
PLFPTYFFPTHSDRKTQNTWINIHYVQSIRSLKDKKCRVNFVDNQSIVVNISAHSMQHQYLNGIYYYYMMDRAARVATFD
PESPIDYTKPQLNIYEALAKYSLFESK
Nucleotide
Download Length: 564 bp
>NTDB_id=838685 QMK35_RS09500 WP_107384866.1 1976563..1977126(-) (comK/comK1) [Staphylococcus cohnii strain SDAQ-1]
ATGATACAACCGTATATTATTAAAAAAGGTGATATGACATTACAACCGTGCCATTTGCCTGTTGGCCAATATGAAGGTAC
ACGAGTACTAAGATATAAAGAAGACGAAAGTACGATAAAAGAACGCACCCACAAAATCATTGATCGTTCTTGTAGATTTT
ATGGTAGTAGCTATGTTTTTAAAAAAGAGGACACAATTCGTATTACAGGCATTAGTAGCAAGCCCCCAATTTTATTTACT
CCATTATTTCCCACTTATTTTTTCCCGACACATTCTGATAGAAAAACACAAAATACATGGATCAATATCCATTATGTTCA
AAGTATTAGATCACTAAAAGATAAAAAATGTAGAGTGAACTTTGTTGATAATCAATCTATCGTTGTGAATATCTCAGCTC
ATAGCATGCAACATCAATATTTAAATGGCATTTATTATTATTATATGATGGATAGAGCAGCAAGAGTTGCCACTTTTGAT
CCAGAGTCTCCCATAGATTACACAAAACCTCAATTAAATATATATGAAGCACTCGCTAAATATTCTTTATTTGAAAGTAA
ATAG
ATGATACAACCGTATATTATTAAAAAAGGTGATATGACATTACAACCGTGCCATTTGCCTGTTGGCCAATATGAAGGTAC
ACGAGTACTAAGATATAAAGAAGACGAAAGTACGATAAAAGAACGCACCCACAAAATCATTGATCGTTCTTGTAGATTTT
ATGGTAGTAGCTATGTTTTTAAAAAAGAGGACACAATTCGTATTACAGGCATTAGTAGCAAGCCCCCAATTTTATTTACT
CCATTATTTCCCACTTATTTTTTCCCGACACATTCTGATAGAAAAACACAAAATACATGGATCAATATCCATTATGTTCA
AAGTATTAGATCACTAAAAGATAAAAAATGTAGAGTGAACTTTGTTGATAATCAATCTATCGTTGTGAATATCTCAGCTC
ATAGCATGCAACATCAATATTTAAATGGCATTTATTATTATTATATGATGGATAGAGCAGCAAGAGTTGCCACTTTTGAT
CCAGAGTCTCCCATAGATTACACAAAACCTCAATTAAATATATATGAAGCACTCGCTAAATATTCTTTATTTGAAAGTAA
ATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
53.005 |
97.861 |
0.519 |
| comK/comK1 | Staphylococcus aureus N315 |
53.005 |
97.861 |
0.519 |