Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   VB057_RS08960 Genome accession   NZ_CP141791
Coordinates   1819096..1819752 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain BHD6     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1814096..1824752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VB057_RS08925 (VB057_08925) dcyD 1814976..1815962 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  VB057_RS08930 (VB057_08930) tcyL 1815977..1816645 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  VB057_RS08935 (VB057_08935) tcyN 1816642..1817394 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  VB057_RS08940 (VB057_08940) sdiA 1817624..1818346 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  VB057_RS08945 (VB057_08945) yecF 1818413..1818637 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  VB057_RS08950 (VB057_08950) yecU 1818624..1818800 (-) 177 WP_001307856.1 protein YecU -
  VB057_RS08955 (VB057_08955) - 1818883..1818954 (-) 72 Protein_1744 transcriptional regulator -
  VB057_RS08960 (VB057_08960) letA 1819096..1819752 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  VB057_RS08965 (VB057_08965) uvrC 1819749..1821581 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  VB057_RS08970 (VB057_08970) pgsA 1821638..1822186 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  VB057_RS08990 (VB057_08990) - 1822880..1823619 (-) 740 Protein_1748 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=838091 VB057_RS08960 WP_000611328.1 1819096..1819752(+) (letA) [Escherichia coli strain BHD6]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=838091 VB057_RS08960 WP_000611328.1 1819096..1819752(+) (letA) [Escherichia coli strain BHD6]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482