Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   VLJ87_RS18075 Genome accession   NZ_CP141770
Coordinates   3978151..3980427 (-) Length   758 a.a.
NCBI ID   WP_003090432.1    Uniprot ID   A0A0H2ZAW8
Organism   Pseudomonas aeruginosa strain PA14-GFP     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3973151..3985427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VLJ87_RS18055 trxB 3975316..3976266 (+) 951 WP_003090421.1 thioredoxin-disulfide reductase -
  VLJ87_RS18060 aat 3976304..3976984 (+) 681 WP_003131120.1 leucyl/phenylalanyl-tRNA--protein transferase -
  VLJ87_RS18065 - 3977039..3977746 (+) 708 WP_003108766.1 arginyltransferase -
  VLJ87_RS18070 infA 3977851..3978069 (+) 219 WP_002553999.1 translation initiation factor IF-1 -
  VLJ87_RS18075 clpC 3978151..3980427 (-) 2277 WP_003090432.1 ATP-dependent Clp protease ATP-binding subunit ClpA Regulator
  VLJ87_RS18080 clpS 3980455..3980823 (-) 369 WP_003097649.1 ATP-dependent Clp protease adapter ClpS -
  VLJ87_RS18085 cspD 3981049..3981321 (+) 273 WP_003090435.1 cold shock domain-containing protein CspD -
  VLJ87_RS18090 icd 3981395..3982651 (-) 1257 WP_003090436.1 NADP-dependent isocitrate dehydrogenase -
  VLJ87_RS18095 - 3983010..3985235 (+) 2226 WP_003090437.1 NADP-dependent isocitrate dehydrogenase -

Sequence

Protein


Download         Length: 758 a.a.        Molecular weight: 84010.68 Da        Isoelectric Point: 5.8904

>NTDB_id=837739 VLJ87_RS18075 WP_003090432.1 3978151..3980427(-) (clpC) [Pseudomonas aeruginosa strain PA14-GFP]
MLNRELEVTLNLAFKEARAKRHEFMTVEHLLLALLDNEAAATVLRACGANLDKLRRDLQEFIDSTTPLIPQHDDERETQP
TLGFQRVLQRAVFHVQSSGKREVTGANVLVAIFSEQESQAVFLLKQQSIARIDVVNYIAHGISKVPGHAEHPQDGEQDMQ
DEEGGESATSNHPLDAYASNLNELARQGRIDPLVGREHEVERVAQILARRRKNNPLLVGEAGVGKTAIAEGLAKRIVDGQ
VPDLLADSVVYSLDLGALLAGTKYRGDFEKRFKALLNELRKRPHAVLFIDEIHTIIGAGAASGGVMDASNLLKPVLSSGE
IRCIGSTTFQEFRGIFEKDRALARRFQKVDVTEPSVEDTYGILKGLKGRFEQHHHIEYSDEALRAAAELAARYINDRHMP
DKAIDVIDEAGAYQRLQPEEKRVKRIEVAQVEDIVAKIARIPPKHVTTSDKELLRNLERDLKLTVFGQDDAIESLSTAIK
LSRAGLKAPDKPVGSFLFAGPTGVGKTEVARQLAKALGVELVRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTEAITK
TPHCVLLLDEIEKAHPEVFNLLLQVMDHGTLTDNNGRKADFRNIILIMTTNAGAEVAARASIGFNQQDHTTDAMEVIKKS
FTPEFRNRLDTIIQFGRLSTETIKSVVDKFLTELQAQLEDKRVQLEVSDAARGWLAEKGYDVQMGARPMARLIQDKIKRP
LAEEILFGELAEHGGLVHVDLKGDELAFEFEITAAEPA

Nucleotide


Download         Length: 2277 bp        

>NTDB_id=837739 VLJ87_RS18075 WP_003090432.1 3978151..3980427(-) (clpC) [Pseudomonas aeruginosa strain PA14-GFP]
ATGTTGAATCGAGAGCTCGAAGTCACCCTCAATCTCGCCTTCAAGGAGGCGAGGGCCAAACGCCATGAATTCATGACGGT
TGAGCACCTGCTGCTGGCCTTGCTGGACAATGAGGCGGCGGCAACGGTATTGCGTGCGTGCGGTGCCAACCTGGACAAGC
TGCGGCGCGACCTGCAGGAATTCATCGATTCCACCACGCCGCTGATCCCGCAGCACGACGACGAGCGCGAAACCCAGCCG
ACGCTGGGCTTCCAGCGCGTCCTGCAGCGTGCGGTGTTCCACGTGCAGAGTTCCGGCAAGCGCGAAGTGACCGGGGCCAA
TGTCCTGGTGGCGATCTTCAGCGAACAGGAAAGCCAGGCGGTGTTCCTGCTCAAGCAGCAGAGCATCGCGCGTATCGATG
TGGTGAACTACATCGCCCACGGCATCTCCAAGGTGCCCGGGCATGCCGAACATCCGCAGGATGGGGAGCAGGATATGCAG
GATGAGGAAGGTGGCGAGTCGGCCACGTCCAACCATCCGCTGGACGCCTATGCCAGCAACCTCAACGAACTGGCTCGCCA
GGGGCGGATCGACCCGCTGGTGGGGCGTGAGCATGAAGTCGAGCGGGTGGCGCAGATCCTTGCCCGCCGGCGCAAGAACA
ACCCGCTGCTGGTAGGCGAGGCGGGGGTCGGCAAGACGGCCATCGCCGAAGGCCTGGCCAAGCGCATCGTCGATGGCCAG
GTGCCGGACCTGCTGGCCGACAGCGTGGTCTACTCCCTCGACCTGGGTGCCTTGCTCGCGGGTACCAAGTACCGCGGCGA
CTTCGAGAAGCGCTTCAAGGCCTTGCTCAACGAGTTGCGCAAGCGCCCGCACGCGGTGCTGTTCATCGACGAGATCCATA
CCATCATCGGCGCCGGTGCAGCATCCGGCGGGGTAATGGACGCCTCCAACCTGCTCAAGCCGGTTCTGTCCTCGGGCGAG
ATCCGCTGCATCGGCTCGACCACCTTCCAGGAGTTCCGCGGCATCTTCGAGAAGGACCGGGCCTTGGCGCGGCGCTTCCA
GAAGGTCGACGTGACCGAGCCGTCGGTGGAAGACACCTATGGCATCCTCAAGGGCCTCAAGGGGCGCTTCGAGCAGCATC
ACCACATCGAGTACAGCGACGAGGCGCTGCGCGCCGCGGCCGAGCTGGCGGCGCGCTACATCAACGACCGGCACATGCCG
GACAAGGCCATCGACGTCATCGACGAGGCGGGCGCCTACCAGCGCCTGCAGCCGGAAGAGAAGCGCGTGAAGCGCATCGA
GGTGGCGCAGGTCGAGGATATCGTGGCGAAGATCGCGCGGATCCCGCCGAAACACGTCACCACCTCGGACAAGGAGTTGC
TGCGCAACCTCGAACGCGACCTCAAGCTGACCGTGTTCGGCCAGGACGACGCCATCGAGTCGCTGTCCACCGCGATCAAG
CTGTCCCGGGCCGGGCTCAAGGCGCCGGACAAGCCGGTCGGCTCGTTCCTCTTCGCCGGTCCCACCGGCGTGGGCAAGAC
CGAAGTGGCGCGGCAGTTGGCGAAGGCCTTGGGCGTGGAACTGGTGCGCTTCGACATGTCCGAGTACATGGAGCGGCATA
CCGTGTCGCGGCTGATCGGTGCGCCTCCGGGCTACGTCGGCTTCGACCAGGGCGGCCTGCTCACCGAGGCGATCACCAAG
ACCCCGCACTGCGTGTTGCTGCTCGACGAGATCGAGAAGGCTCACCCGGAGGTCTTCAACCTGCTGCTGCAGGTGATGGA
CCACGGCACCCTGACCGACAACAACGGGCGCAAGGCGGACTTCCGCAACATCATCCTGATCATGACCACCAACGCCGGCG
CGGAAGTGGCGGCGCGCGCGTCGATCGGCTTCAACCAGCAGGATCACACCACCGATGCGATGGAAGTGATCAAGAAGAGC
TTCACCCCGGAGTTCCGCAACCGCCTGGATACCATCATCCAGTTCGGCCGCCTGAGCACCGAGACGATCAAGAGCGTGGT
CGACAAGTTCCTCACCGAGCTGCAGGCGCAGCTGGAGGACAAGCGCGTCCAGCTCGAGGTCAGCGATGCGGCGCGCGGCT
GGCTGGCGGAGAAGGGCTACGACGTGCAGATGGGTGCGCGACCGATGGCGCGGCTTATCCAGGACAAGATCAAGCGGCCG
TTGGCCGAGGAGATCCTGTTCGGCGAGCTGGCCGAGCATGGCGGCCTGGTGCATGTCGACCTGAAGGGCGACGAGCTGGC
CTTCGAGTTCGAGATCACGGCGGCGGAGCCCGCCTGA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(216-328)

AAA lid domain (AAA_lid_9)

(355-458)

AAA domain (Cdc48 subfamily) (AAA_2)

(491-652)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(13-62)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-739)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZAW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

38.956

100

0.423
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.667

96.57

0.402
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

37.247

100

0.389
  clpC Streptococcus mutans UA159

45.484

81.794

0.372
  clpC Lactococcus lactis subsp. cremoris KW2

44.586

82.85

0.369