Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   QN289_RS03440 Genome accession   NZ_CP126312
Coordinates   662555..663430 (+) Length   291 a.a.
NCBI ID   WP_039099523.1    Uniprot ID   -
Organism   Latilactobacillus curvatus strain KFRI-K200347     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 657555..668430
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN289_RS03400 (QN289_03400) - 657660..658487 (-) 828 WP_039099661.1 LysR family transcriptional regulator -
  QN289_RS03405 (QN289_03405) - 658596..659609 (+) 1014 WP_004265264.1 YeiH family protein -
  QN289_RS03410 (QN289_03410) - 659700..659939 (-) 240 WP_004270892.1 cytochrome b5 domain-containing protein -
  QN289_RS03415 (QN289_03415) - 660134..660469 (+) 336 WP_146954925.1 hypothetical protein -
  QN289_RS03425 (QN289_03425) - 660650..661027 (-) 378 WP_004270910.1 hypothetical protein -
  QN289_RS03430 (QN289_03430) - 661130..661630 (+) 501 WP_004270893.1 VanZ family protein -
  QN289_RS03435 (QN289_03435) - 661720..662451 (+) 732 WP_004270897.1 YebC/PmpR family DNA-binding transcriptional regulator -
  QN289_RS03440 (QN289_03440) comGA 662555..663430 (+) 876 WP_039099523.1 competence type IV pilus ATPase ComGA Machinery gene
  QN289_RS03445 (QN289_03445) comGB 663420..664421 (+) 1002 WP_146954924.1 type II secretion system F family protein Machinery gene
  QN289_RS03450 (QN289_03450) - 664474..665937 (-) 1464 WP_284182907.1 recombinase family protein -
  QN289_RS03455 (QN289_03455) - 666027..666617 (-) 591 WP_284182908.1 DUF5067 domain-containing protein -
  QN289_RS03460 (QN289_03460) - 666692..667093 (-) 402 WP_284182909.1 ImmA/IrrE family metallo-endopeptidase -
  QN289_RS03465 (QN289_03465) - 667095..667430 (-) 336 WP_259770237.1 helix-turn-helix transcriptional regulator -
  QN289_RS03470 (QN289_03470) - 667579..667806 (+) 228 WP_284182910.1 helix-turn-helix transcriptional regulator -
  QN289_RS03475 (QN289_03475) - 667825..667989 (+) 165 WP_284182911.1 hypothetical protein -

Sequence

Protein


Download         Length: 291 a.a.        Molecular weight: 32042.84 Da        Isoelectric Point: 5.5654

>NTDB_id=837527 QN289_RS03440 WP_039099523.1 662555..663430(+) (comGA) [Latilactobacillus curvatus strain KFRI-K200347]
MTEVLTTLLQKCATEKAQDLYFRPLSTGWAIIERLATGLKPLQKVTLSEGNQWLNQMKYQAGMDISETRRPQTGRSAIEV
AGELIYLRLATVGDFLNRESLVVRFIYPIGQTYHCDDSQILSRLMQLIQQPGLLLFAGPTGSGKTTSLYYLAEQVMQDKM
VVAIEDPIEIQQPAFLQLQVNEAAGLTYAALLKISLRLRPDTLIIGEIRDLQTAQHAVSAALSGHLVLSTIHARSTTGVM
DRLLDLGISHSQLTACLAGVAYQSLVVDGHNVAAHYELATAQQLEEAVHED

Nucleotide


Download         Length: 876 bp        

>NTDB_id=837527 QN289_RS03440 WP_039099523.1 662555..663430(+) (comGA) [Latilactobacillus curvatus strain KFRI-K200347]
ATGACCGAAGTATTAACAACCCTTTTGCAAAAGTGCGCAACGGAAAAAGCGCAGGATCTTTATTTTCGACCACTATCGAC
GGGTTGGGCAATTATTGAACGCTTAGCGACAGGACTAAAGCCGTTACAAAAAGTTACTCTGTCAGAAGGCAATCAATGGC
TCAATCAAATGAAGTATCAAGCGGGGATGGATATCAGTGAAACTCGGCGTCCACAGACCGGCCGTTCAGCGATCGAGGTG
GCAGGCGAATTGATTTATTTACGGTTGGCAACCGTGGGGGATTTTTTGAATCGGGAAAGTTTAGTTGTTCGTTTCATTTA
TCCCATTGGGCAGACTTATCATTGCGACGACTCGCAGATTTTAAGTCGTTTAATGCAGTTAATTCAGCAACCAGGATTAT
TGCTATTTGCCGGTCCAACTGGTTCAGGGAAGACAACAAGTTTGTACTATCTTGCGGAACAAGTCATGCAAGATAAGATG
GTGGTTGCGATTGAAGATCCGATAGAGATTCAACAGCCAGCGTTCTTACAGTTACAAGTGAATGAAGCCGCAGGGTTAAC
CTATGCAGCATTGTTGAAAATCAGTTTGCGATTACGGCCTGATACCTTAATTATTGGTGAGATTCGCGACTTACAGACGG
CCCAACACGCGGTTTCTGCGGCGTTGAGCGGTCACTTGGTACTAAGTACGATTCACGCGCGAAGTACAACGGGGGTGATG
GACCGTCTATTAGATCTTGGAATTAGCCACTCACAATTAACCGCTTGTTTAGCGGGTGTTGCCTATCAATCACTAGTGGT
CGACGGCCACAATGTAGCGGCCCACTATGAGTTAGCAACTGCACAACAATTGGAGGAGGCTGTTCATGAAGACTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Latilactobacillus sakei subsp. sakei 23K

69.892

95.876

0.67
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

43.015

93.471

0.402
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

42.593

92.784

0.395
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

41.573

91.753

0.381
  comGA/cglA/cilD Streptococcus pneumoniae R6

41.573

91.753

0.381
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

41.573

91.753

0.381
  comGA/cglA/cilD Streptococcus pneumoniae D39

41.573

91.753

0.381
  comGA Lactococcus lactis subsp. cremoris KW2

41.603

90.034

0.375
  comYA Streptococcus mutans UA140

37.113

100

0.371
  comYA Streptococcus mutans UA159

37.113

100

0.371
  comYA Streptococcus gordonii str. Challis substr. CH1

39.194

93.814

0.368