Detailed information NTG0836559

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: U5072_RS16710
• Genome accession: NZ_CP141222
• Coordinates: 3869293..3870414 (-)
• Length: 373 a.a.
• NCBI ID: WP_031136173.1
• Uniprot ID: A0A1D8G486
• Organism: Streptomyces sp. SS162
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3864293..3875414

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U5072_RS16690 (U5072_16690)	-	3864944..3865669 (-)	726	WP_331453068.1	SigE family RNA polymerase sigma factor	-
U5072_RS16695 (U5072_16695)	-	3866155..3867114 (-)	960	WP_249467631.1	A/G-specific adenine glycosylase	-
U5072_RS16700 (U5072_16700)	-	3867384..3868076 (-)	693	WP_037939586.1	phosphatase PAP2 family protein	-
U5072_RS16705 (U5072_16705)	-	3868246..3869133 (+)	888	WP_331453069.1	hypothetical protein	-
U5072_RS16710 (U5072_16710)	disA	3869293..3870414 (-)	1122	WP_031136173.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
U5072_RS16715 (U5072_16715)	radA/sms	3870738..3872141 (-)	1404	WP_031136171.1	DNA repair protein RadA	Machinery gene
U5072_RS16720 (U5072_16720)	-	3872350..3874395 (+)	2046	WP_331453070.1	hypothetical protein	-
U5072_RS16725 (U5072_16725)	-	3874472..3875296 (-)	825	WP_331454005.1	hypothetical protein	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40188.06 Da
• Isoelectric Point: 5.0196

>NTDB_id=836559 U5072_RS16710 WP_031136173.1 3869293..3870414(-) (disA) [Streptomyces sp. SS162]
MAANDRATPGKSGGGSGNEALMRASLSAVAPGTALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLNVEFTATRLRE
LCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSRQCGFPVISVSQSMRLIALYVDGERRVLEESAAI
LSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIAG
VEPERELVVRDYVPEPTAKRSRTVAEALTELDALSHAELLELPTVARALGYSGSPETLDSAVSPRGYRLLAKVPRLPGAI
IERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=836559 U5072_RS16710 WP_031136173.1 3869293..3870414(-) (disA) [Streptomyces sp. SS162]
GTGGCAGCCAACGACCGGGCAACACCCGGAAAGTCGGGCGGAGGCTCCGGCAACGAAGCGCTGATGCGCGCGTCCCTCAG
TGCGGTCGCCCCCGGCACGGCGCTGCGGGACGGACTGGAGCGCATCCTCCGCGGCAACACGGGCGGTCTGATCGTCCTCG
GCATGGACAAGACGGTCGAGTCGATGTGCACCGGCGGTTTCGTGCTGAACGTCGAGTTCACCGCGACCCGTCTGCGCGAG
CTGTGCAAGCTCGACGGCGCGCTCATCCTGGACAAGGACATCACCAAGATCCTGCGCGCCGGTGTCCAGCTCGTGCCCGA
CGCGTCCATCCCGACCGAGGAGACCGGCACACGGCACCGCACGGCGGACCGGGTGTCCAGGCAGTGCGGCTTCCCCGTGA
TCTCCGTGTCCCAGTCGATGCGGCTGATCGCCCTCTACGTGGACGGCGAGCGCCGCGTCCTGGAGGAGTCCGCCGCGATC
CTGTCGCGGGCCAACCAGGCCCTCGCCACCCTGGAGCGGTACAAGCTGCGCCTGGACGAGGTGGCCGGGACGCTCTCCGC
GCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTCACGGCCGTGGCGCAGCGGCTGGAGATGGTCCGCCGCATCGCCA
CGGAGATCGCGGAGTACGTGGTCGAGCTCGGCACCGACGGGCGCCTCCTCGCCCTCCAGTTGGACGAGCTGATCGCGGGT
GTGGAGCCCGAGCGGGAGCTGGTGGTGCGGGACTACGTGCCCGAGCCGACCGCGAAGCGGTCCCGTACGGTCGCCGAGGC
GCTGACCGAGCTGGACGCCCTGTCGCACGCCGAGCTGCTGGAGCTGCCGACGGTGGCCCGCGCCCTCGGCTACAGCGGCT
CGCCCGAGACCCTCGACTCGGCCGTGTCGCCGCGCGGCTACCGCCTGCTGGCGAAGGTGCCGCGCCTGCCCGGCGCGATC
ATCGAGCGGCTCGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTGGCCGCGAGTGTGGACGACCTCCAGACCGTGGACGG
CGTCGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGCCTGTCCCGGCTGGCCGAGTCCTCGATCCTCGAACGCTACGTCT
GA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (323-358)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (37-150)

• DisA bacterial checkpoint controller linker region (DisA-linker) (154-296)

3D structure

• AlphaFold DB: A0A1D8G486

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.783	0.448