Detailed information NTG0836186

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: U8P27_RS19315
• Genome accession: NZ_CP141093
• Coordinates: 3939163..3941439 (-)
• Length: 758 a.a.
• NCBI ID: WP_001538509.1
• Uniprot ID: -
• Organism: Escherichia coli strain KE41
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3934163..3946439

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U8P27_RS19295 (U8P27_19295)	cydC	3935449..3937170 (+)	1722	WP_001202199.1	heme ABC transporter ATP-binding protein/permease CydC	-
U8P27_RS19300 (U8P27_19300)	aat	3937212..3937916 (+)	705	WP_001241673.1	leucyl/phenylalanyl-tRNA--protein transferase	-
U8P27_RS19305 (U8P27_19305)	infA	3938201..3938419 (+)	219	WP_001040187.1	translation initiation factor IF-1	-
U8P27_RS19315 (U8P27_19315)	clpC	3939163..3941439 (-)	2277	WP_001538509.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
U8P27_RS19320 (U8P27_19320)	clpS	3941470..3941790 (-)	321	WP_001538508.1	ATP-dependent Clp protease adapter ClpS	-
U8P27_RS19325 (U8P27_19325)	yljB	3941889..3941963 (-)	75	WP_001406719.1	protein YljB	-
U8P27_RS19330 (U8P27_19330)	cspD	3942113..3942337 (+)	225	WP_000410785.1	cold shock-like protein CspD	-
U8P27_RS19335 (U8P27_19335)	macB	3942410..3944356 (-)	1947	WP_001538507.1	macrolide ABC transporter ATP-binding protein/permease MacB	-
U8P27_RS19340 (U8P27_19340)	macA	3944353..3945468 (-)	1116	WP_000746478.1	macrolide transporter subunit MacA	-

Sequence

Protein

• Length: 758 a.a.
• Molecular weight: 84206.93 Da
• Isoelectric Point: 6.2512

>NTDB_id=836186 U8P27_RS19315 WP_001538509.1 3939163..3941439(-) (clpC) [Escherichia coli strain KE41]
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQP
TLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVM
ADCTLYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIG
STTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAID
VIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAG
LGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAV
LLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEF
RNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANEL
LFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH

Nucleotide

• Length: 2277 bp

>NTDB_id=836186 U8P27_RS19315 WP_001538509.1 3939163..3941439(-) (clpC) [Escherichia coli strain KE41]
ATGCTCAATCAAGAACTGGAACTCAGTTTAAATATGGCTTTCGCCAGAGCGCGCGAGCACCGTCATGAGTTTATGACCGT
CGAGCACTTGTTACTGGCGCTGCTCAGTAACCCATCTGCCCGGGAGGCGCTGGAAGCGTGTTCTGTGGATTTGGTTGCGC
TCCGTCAGGAACTGGAAGCCTTTATTGAACAAACCACACCCGTTCTGCCTGCCAGTGAAGAGGAGCGCGACACACAACCG
ACGCTGAGTTTTCAGCGTGTACTGCAACGTGCGGTCTTCCATGTCCAGTCCTCCGGTCGCAATGAGGTTACCGGTGCAAA
CGTTCTGGTCGCTATCTTTAGCGAACAGGAGTCGCAGGCGGCATATCTGTTGCGCAAACATGAAGTCAGCCGTCTCGATG
TGGTGAACTTTATCTCTCATGGCACGCGTAAAGACGAGCCGACACAGTCTTCTGATCCTGGCAGCCAGCCAAACAGCGAA
GAACAAGCTGGTGGGGAGGAACGTATGGAGAATTTCACGACGAACCTGAATCAGCTTGCGCGAGTGGGCGGAATCGACCC
ACTGATTGGTCGTGAGAAGGAGCTGGAGCGTGCTATTCAGGTTCTCTGCCGTCGCCGTAAAAACAACCCGCTGCTGGTGG
GGGAGTCTGGTGTCGGTAAAACCGCGATTGCGGAGGGGCTTGCATGGCGAATTGTTCAGGGCGATGTGCCGGAAGTGATG
GCTGACTGTACGCTTTACTCTCTCGATATCGGTTCCCTGTTAGCGGGCACAAAATATCGCGGCGACTTTGAAAAACGTTT
TAAAGCGTTGCTCAAGCAGCTGGAGCAGGACACTAACAGCATCCTGTTTATTGATGAGATCCACACCATTATCGGTGCGG
GTGCAGCGTCTGGTGGCCAGGTCGATGCGGCTAACCTGATTAAACCGTTGCTCTCCAGCGGTAAAATCCGCGTAATTGGT
TCGACAACCTATCAGGAGTTCAGCAACATTTTTGAGAAAGACCGTGCTCTGGCGCGTCGCTTCCAGAAAATTGATATTAC
TGAACCGTCAATCGAAGAAACTGTTCAAATCATCAATGGCCTGAAACCGAAGTATGAAGCGCACCACGACGTGCGTTATA
CCGCAAAAGCGGTGCGTGCGGCGGTAGAGCTGGCGGTGAAATACATTAACGATCGTCATCTGCCGGATAAAGCGATTGAT
GTTATCGACGAAGCGGGCGCTCGCGCACGTCTGATGCCGGTAAGCAAACGCAAGAAAACCGTTAATGTGGCGGATATTGA
ATCCGTGGTGGCCCGTATTGCACGCATTCCAGAGAAGAGTGTTTCTCAGAGTGACCGCGATACCCTGAAAAACCTCGGCG
ATCGCCTGAAAATGCTGGTCTTCGGTCAGGATAAAGCCATTGAGGCGCTGACTGAAGCCATTAAGATGGCGCGTGCAGGT
TTAGGTCACGAACATAAACCGGTCGGTTCGTTCCTGTTTGCCGGCCCTACTGGGGTCGGGAAAACAGAGGTGACGGTACA
GCTTTCGAAAGCGTTGGGCATTGAGCTTCTGCGCTTTGATATGTCCGAGTATATGGAACGCCATACCGTCAGCCGTCTGA
TTGGTGCGCCTCCGGGATACGTTGGTTTTGATCAGGGCGGTTTGCTGACTGATGCGGTCATCAAGCATCCACATGCGGTG
CTGCTGCTGGACGAAATCGAGAAAGCGCACCCGGACGTGTTCAACATCCTCTTGCAGGTGATGGACAACGGTACACTGAC
CGATAACAACGGACGCAAAGCGGACTTCCGTAACGTGGTGCTGGTGATGACCACTAACGCGGGGGTACGTGAAACCGAGC
GCAAATCCATTGGTCTTATCCACCAGGATAACAGCACCGATGCGATGGAAGAGATCAAGAAGATCTTTACACCGGAATTC
CGTAACCGTCTCGACAACATTATCTGGTTCGATCATCTGTCAACCGACGTGATCCATCAGGTGGTGGATAAATTCATCGT
CGAGTTGCAGGTTCAGTTGGATCAGAAAGGTGTTTCTCTGGAAGTGAGCCAGGAAGCGCGTAACTGGCTGGCCGAGAAAG
GTTACGACCGGGCAATGGGCGCACGTCCGATGGCGCGTGTCATCCAGGACAACCTGAAAAAACCGCTCGCCAACGAACTG
CTGTTTGGTTCGCTGGTGGACGGCGGTCAGGTCACCGTCGCGCTGGATAAAGAGAAAAATGAGCTGACTTACGGATTCCA
GAGTGCACAAAAGCACAAGGCGGAAGCAGCGCATTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (350-452)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-733)

• AAA domain (Cdc48 subfamily) (AAA_2) (486-647)

• ATPase family associated with various cellular activities (AAA) (AAA) (211-342)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	38.868	100	0.408
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.209	96.042	0.396
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	35.337	100	0.38
clpC	Streptococcus thermophilus LMD-9	42.222	89.05	0.376
clpC	Streptococcus thermophilus LMG 18311	42.074	89.05	0.375
clpC	Streptococcus mutans UA159	39.407	93.404	0.368