Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   QM339_RS06160 Genome accession   NZ_CP125899
Coordinates   1247177..1248151 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain CHAL3     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1242177..1253151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QM339_RS06120 (QM339_06120) gcvT 1242678..1243769 (-) 1092 WP_000093344.1 glycine cleavage system aminomethyltransferase GcvT -
  QM339_RS06125 (QM339_06125) - 1243928..1244452 (-) 525 WP_001015120.1 shikimate kinase -
  QM339_RS06130 (QM339_06130) - 1244442..1244588 (-) 147 WP_001789879.1 hypothetical protein -
  QM339_RS06135 (QM339_06135) comGF 1244685..1245182 (-) 498 WP_001796472.1 competence type IV pilus minor pilin ComGF Machinery gene
  QM339_RS06140 (QM339_06140) comGE 1245100..1245399 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  QM339_RS06145 (QM339_06145) comGD 1245386..1245832 (-) 447 WP_283502335.1 competence type IV pilus minor pilin ComGD Machinery gene
  QM339_RS06150 (QM339_06150) comGC 1245810..1246121 (-) 312 WP_000472255.1 competence type IV pilus major pilin ComGC Machinery gene
  QM339_RS06155 (QM339_06155) comGB 1246135..1247205 (-) 1071 WP_000776409.1 competence type IV pilus assembly protein ComGB Machinery gene
  QM339_RS06160 (QM339_06160) comGA 1247177..1248151 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  QM339_RS06165 (QM339_06165) - 1248203..1248826 (-) 624 WP_001223009.1 MBL fold metallo-hydrolase -
  QM339_RS06170 (QM339_06170) - 1248823..1249152 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  QM339_RS06175 (QM339_06175) - 1249152..1250138 (-) 987 WP_000161307.1 ROK family glucokinase -
  QM339_RS06180 (QM339_06180) - 1250135..1250338 (-) 204 WP_000087561.1 YqgQ family protein -
  QM339_RS06185 (QM339_06185) - 1250319..1251782 (-) 1464 WP_283502336.1 rhomboid family intramembrane serine protease -
  QM339_RS06190 (QM339_06190) - 1251794..1252333 (-) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  QM339_RS06195 (QM339_06195) rpmG 1252542..1252691 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=833513 QM339_RS06160 WP_000697220.1 1247177..1248151(-) (comGA) [Staphylococcus aureus strain CHAL3]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=833513 QM339_RS06160 WP_000697220.1 1247177..1248151(-) (comGA) [Staphylococcus aureus strain CHAL3]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGACTTGATGTATCTACACAACAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTGATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1