NTDB

Overview

Name	coiA	Type	Machinery gene
Locus tag	QM316_RS05590	Genome accession	NZ_CP125862
Coordinates	1110739..1111725 (-)	Length	328 a.a.
NCBI ID	WP_000959278.1	Uniprot ID	A0A6B5F529
Organism	Staphylococcus aureus strain 18-02202-1
Function	require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1105739..1116725

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QM316_RS05565 (QM316_05560)	-	1105998..1106345 (-)	348	WP_001242107.1	hypothetical protein	-
QM316_RS05570 (QM316_05565)	-	1106531..1107124 (+)	594	WP_000224616.1	CYTH domain-containing protein	-
QM316_RS05575 (QM316_05570)	-	1107228..1107593 (+)	366	WP_000214067.1	truncated hemoglobin YjbI	-
QM316_RS05580 (QM316_05575)	yjbH	1107616..1108422 (+)	807	WP_000896694.1	protease adaptor protein YjbH	-
QM316_RS05585 (QM316_05580)	pepF	1108883..1110691 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
QM316_RS05590 (QM316_05585)	coiA	1110739..1111725 (-)	987	WP_000959278.1	competence protein CoiA family protein	Machinery gene
QM316_RS05595 (QM316_05590)	mecA	1111846..1112565 (-)	720	WP_001217725.1	adaptor protein MecA	-
QM316_RS05600 (QM316_05595)	spxA	1112946..1113341 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
QM316_RS05605 (QM316_05600)	trpS	1113636..1114625 (+)	990	WP_000448929.1	tryptophan--tRNA ligase	-
QM316_RS05610 (QM316_05605)	opp4C	1114667..1115548 (-)	882	WP_001180269.1	oligopeptide ABC transporter permease	-
QM316_RS05615 (QM316_05610)	opp4B	1115560..1116522 (-)	963	WP_000593418.1	oligopeptide ABC transporter permease	-

Sequence

Protein

Download Length: 328 a.a. Molecular weight: 38679.31 Da Isoelectric Point: 9.5882

                                >NTDB_id=833109 QM316_RS05590 WP_000959278.1 1110739..1111725(-) (coiA) [Staphylococcus aureus strain 18-02202-1]

MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNESIKHYKSKLILAQMIQQQGCKV

EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSMFINPITRKL

HTFNLEKKQIMMFQQIQYIGGHKYVAEKGNAKISELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ

LTVQEVVHNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLLSDNLNYFKLKKFIVALDSKTAIIEKLINNYLNICSDR

GNDVQILF

Nucleotide

Download Length: 987 bp

                                >NTDB_id=833109 QM316_RS05590 WP_000959278.1 1110739..1111725(-) (coiA) [Staphylococcus aureus strain 18-02202-1]

ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGCGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCGGT

GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT

GTTTTAATAATGAATCGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA

GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA

TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA

ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCAAAGTATGTTTATTAATCCAATCACTCGAAAACTT

CATACGTTTAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATATAGGCGGGCACAAATATGTCGCTGA

AAAAGGGAATGCCAAAATTAGTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTTG

CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAGTTACAG

TTAACTGTTCAAGAAGTAGTGCACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG

GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTACTAAGTGACAATCTTAATTATTTTAAACTGAAAA

AGTTTATTGTTGCTCTAGATAGCAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA

GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-288)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A6B5F529

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
coiA	Staphylococcus aureus N315	96.646	100	0.966
coiA	Staphylococcus aureus MW2	96.646	100	0.966

Detailed information NTG0833109