Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I3F59_RS24555 Genome accession   NZ_CP140097
Coordinates   5588561..5589220 (-) Length   219 a.a.
NCBI ID   WP_240134418.1    Uniprot ID   A0ABT6HIE9
Organism   Streptomyces sp. MUM 178J     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5583561..5594220
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3F59_RS24535 (I3F59_024535) - 5583904..5584872 (+) 969 WP_240134414.1 ABC transporter ATP-binding protein -
  I3F59_RS24540 (I3F59_024540) - 5584869..5586545 (+) 1677 WP_240134415.1 ABC transporter permease -
  I3F59_RS24545 (I3F59_024545) - 5586644..5587867 (-) 1224 WP_240134416.1 cytochrome P450 -
  I3F59_RS24550 (I3F59_024550) - 5587932..5588423 (-) 492 WP_240134417.1 hypothetical protein -
  I3F59_RS24555 (I3F59_024555) vraR 5588561..5589220 (-) 660 WP_240134418.1 response regulator transcription factor Regulator
  I3F59_RS24560 (I3F59_024560) - 5589217..5590554 (-) 1338 WP_240134419.1 histidine kinase -
  I3F59_RS24565 (I3F59_024565) - 5590629..5590805 (-) 177 WP_240134420.1 hypothetical protein -
  I3F59_RS24570 (I3F59_024570) - 5590859..5591749 (-) 891 WP_240134421.1 alpha/beta hydrolase -
  I3F59_RS24575 (I3F59_024575) kynU 5592175..5593365 (-) 1191 WP_240134422.1 kynureninase -
  I3F59_RS24580 (I3F59_024580) - 5593358..5594176 (-) 819 WP_240134423.1 tryptophan 2,3-dioxygenase family protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23701.53 Da        Isoelectric Point: 4.6337

>NTDB_id=833086 I3F59_RS24555 WP_240134418.1 5588561..5589220(-) (vraR) [Streptomyces sp. MUM 178J]
MTIRVLVVDDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVARVAELTPDVVLMDIRMPELNGIEATREITALHADSKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPTVTRRLITEFSKLPQTPKPPAMAQIGDLTERE
TEVLVLIAQGLSNAEIAELLVVAESTIKTHVSRVLVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 660 bp        

>NTDB_id=833086 I3F59_RS24555 WP_240134418.1 5588561..5589220(-) (vraR) [Streptomyces sp. MUM 178J]
ATGACGATCCGGGTGCTGGTCGTCGACGACCAGATGATGGTGCGCGAGGGCTTCTCGGTCCTGTTGAACGCGATGCCGGA
CATCGAGGTCGTCGGCGAGGCGGTGAACGGCCGTGAGGCGGTCGCCAGGGTCGCCGAGCTGACGCCAGACGTGGTGCTGA
TGGACATCCGCATGCCGGAGCTCAACGGCATCGAGGCGACGCGGGAGATCACGGCGCTGCACGCCGACTCCAAGGTGCTG
GTGCTGACCACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCCGGGGCGTCGGGCTTTCTGCTCAAGGACGC
CTCCGCGCGCCAGCTCGCCGACGGGGTGCGTGTGGTGGCGGCGGGCGAGGCGCTGCTCGCCCCGACGGTCACCCGCCGTC
TGATCACGGAGTTCTCCAAGCTGCCGCAGACGCCCAAGCCGCCTGCCATGGCGCAGATCGGCGATCTGACGGAGCGTGAG
ACGGAGGTGCTGGTGCTGATCGCCCAGGGGTTGTCCAACGCGGAGATCGCCGAGCTTCTGGTCGTCGCGGAGTCGACCAT
CAAGACCCATGTGAGCCGGGTCCTGGTGAAGCTCGGGCTGCGGGACCGCACCCAGGCGGCGGTGTTCGCATACGAGGCCC
GGCTGGTCACACCGGGGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.907

98.63

0.443
  degU Bacillus subtilis subsp. subtilis str. 168

42.396

99.087

0.42