Detailed information NTG0833085

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QM316_RS00525
• Genome accession: NZ_CP125862
• Coordinates: 94790..95833 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 18-02202-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 89790..100833

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QM316_RS00495 (QM316_00490)	-	90351..90461 (+)	111	WP_001790257.1	hypothetical protein	-
QM316_RS00500 (QM316_00495)	-	90490..90903 (+)	414	WP_025174475.1	hypothetical protein	-
QM316_RS00505 (QM316_00500)	-	91092..92078 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
QM316_RS00510 (QM316_00505)	map	92716..93474 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QM316_RS00515 (QM316_00510)	-	93691..94077 (+)	387	WP_001110179.1	hypothetical protein	-
QM316_RS00520 (QM316_00515)	liaF	94092..94793 (+)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
QM316_RS00525 (QM316_00520)	vraS	94790..95833 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QM316_RS00530 (QM316_00525)	vraR	95823..96452 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
QM316_RS00535 (QM316_00530)	-	96565..97782 (-)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
QM316_RS00540 (QM316_00535)	-	98060..98335 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
QM316_RS00545 (QM316_00540)	-	98342..98806 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QM316_RS00550 (QM316_00545)	-	98953..99153 (+)	201	WP_000180462.1	DUF1128 family protein	-
QM316_RS00555 (QM316_00550)	-	99156..100412 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=833085 QM316_RS00525 WP_001017131.1 94790..95833(+) (vraS) [Staphylococcus aureus strain 18-02202-1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=833085 QM316_RS00525 WP_001017131.1 94790..95833(+) (vraS) [Staphylococcus aureus strain 18-02202-1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATT
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCGGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1