Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I3F59_RS13680 Genome accession   NZ_CP140097
Coordinates   3123812..3124489 (-) Length   225 a.a.
NCBI ID   WP_240140222.1    Uniprot ID   A0ABT6HKB4
Organism   Streptomyces sp. MUM 178J     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3118812..3129489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3F59_RS13660 (I3F59_013660) - 3119853..3120530 (-) 678 WP_240135075.1 ABC transporter ATP-binding protein -
  I3F59_RS13665 (I3F59_013665) - 3120527..3121570 (-) 1044 WP_240135074.1 ABC transporter permease -
  I3F59_RS13670 (I3F59_013670) - 3121683..3122855 (+) 1173 WP_240135073.1 sensor histidine kinase -
  I3F59_RS13675 (I3F59_013675) - 3122852..3123487 (+) 636 WP_240135072.1 response regulator transcription factor -
  I3F59_RS13680 (I3F59_013680) vraR 3123812..3124489 (-) 678 WP_240140222.1 response regulator transcription factor Regulator
  I3F59_RS13685 (I3F59_013685) - 3124486..3125748 (-) 1263 WP_240140221.1 sensor histidine kinase -
  I3F59_RS13690 (I3F59_013690) - 3126155..3128314 (+) 2160 WP_240140220.1 MMPL family transporter -
  I3F59_RS13695 (I3F59_013695) - 3128424..3129017 (+) 594 WP_240140219.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24239.78 Da        Isoelectric Point: 5.1598

>NTDB_id=833057 I3F59_RS13680 WP_240140222.1 3123812..3124489(-) (vraR) [Streptomyces sp. MUM 178J]
MTISVAVVDDQALVRGGFAMILRVHQDIEVVAEAGTGLEAVEAARRHRPDVILMDIRMPEMDGLEATSRILAEADWDVRV
LILTTFDPDEYVYRALRAGASAFVLKDIPPEQLADAVRTVADGGALLAPSITRRLIGRFSERPAVNAAVAARLERLTERE
REVAAAVARGASNSEIAADLRIGAATVKSHVSSILVKLGLRDRTQVVIFAYESGLVEAGVHDIGH

Nucleotide


Download         Length: 678 bp        

>NTDB_id=833057 I3F59_RS13680 WP_240140222.1 3123812..3124489(-) (vraR) [Streptomyces sp. MUM 178J]
GTGACCATCAGCGTCGCCGTCGTCGACGACCAGGCACTGGTCCGCGGAGGCTTTGCGATGATCCTCCGGGTCCATCAGGA
CATCGAGGTGGTCGCCGAGGCCGGAACCGGCCTCGAAGCGGTCGAGGCGGCACGACGGCACCGGCCCGATGTGATCCTCA
TGGACATCCGGATGCCCGAGATGGACGGGCTGGAAGCCACCTCCCGCATCCTCGCCGAAGCGGACTGGGACGTCCGGGTG
CTGATCCTGACCACGTTCGACCCGGACGAGTACGTCTACCGGGCGCTGCGCGCGGGAGCCAGCGCCTTTGTGCTCAAGGA
CATCCCTCCCGAGCAACTCGCCGACGCGGTCCGCACCGTGGCGGACGGCGGAGCCCTGTTGGCGCCGTCCATCACCCGGC
GTCTCATCGGCAGGTTCAGCGAGCGCCCCGCCGTCAACGCGGCCGTCGCCGCCCGGCTGGAGAGGCTCACCGAACGGGAG
CGCGAGGTGGCGGCCGCCGTCGCGCGCGGGGCCAGCAACTCGGAGATCGCCGCAGACCTCCGCATCGGCGCGGCGACCGT
CAAGTCGCATGTGTCGAGCATCCTGGTGAAGCTGGGGCTGCGCGACCGCACCCAGGTGGTGATCTTCGCCTACGAGAGCG
GCCTCGTCGAGGCGGGCGTCCACGACATCGGCCACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.857

96.444

0.413
  degU Bacillus subtilis subsp. subtilis str. 168

39.111

100

0.391