Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R8624_RS01825 Genome accession   NZ_AP026930
Coordinates   351683..352315 (+) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701208     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 346683..357315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8624_RS01800 (PC1195_03450) mvaD 346960..347913 (+) 954 WP_000373460.1 diphosphomevalonate decarboxylase -
  R8624_RS01805 (PC1195_03460) - 347900..348907 (+) 1008 WP_000562436.1 phosphomevalonate kinase -
  R8624_RS01810 (PC1195_03470) fni 348891..349901 (+) 1011 WP_000210610.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R8624_RS01815 (PC1195_03480) liaF 349979..350677 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  R8624_RS01820 (PC1195_03490) - 350674..351669 (+) 996 WP_000743662.1 sensor histidine kinase -
  R8624_RS01825 (PC1195_03500) vraR 351683..352315 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  R8624_RS01830 - 352316..352558 (+) 243 Protein_358 DNA alkylation repair protein -
  R8624_RS01835 - 352483..353085 (+) 603 Protein_359 DNA alkylation repair protein -
  R8624_RS01840 (PC1195_03530) - 353544..354146 (+) 603 Protein_360 trypsin-like serine peptidase -
  R8624_RS01845 (PC1195_03540) - 354502..354807 (+) 306 WP_001821501.1 tyrosine-type recombinase/integrase -
  R8624_RS01850 (PC1195_03550) tig 355001..356284 (+) 1284 WP_000116462.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=83254 R8624_RS01825 WP_000698433.1 351683..352315(+) (vraR) [Streptococcus pneumoniae strain PZ900701208]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=83254 R8624_RS01825 WP_000698433.1 351683..352315(+) (vraR) [Streptococcus pneumoniae strain PZ900701208]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment