Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   U0450_RS06665 Genome accession   NZ_CP139863
Coordinates   1317935..1318834 (+) Length   299 a.a.
NCBI ID   WP_050115346.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P2112     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1312935..1323834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS06635 - 1313105..1313398 (+) 294 WP_000977368.1 hypothetical protein -
  U0450_RS06640 - 1313554..1314768 (+) 1215 WP_000666469.1 pyridoxal phosphate-dependent aminotransferase -
  U0450_RS06645 rpmH 1314913..1315047 (+) 135 WP_000831905.1 50S ribosomal protein L34 -
  U0450_RS06650 - 1315248..1316225 (+) 978 Protein_1285 DUF1542 domain-containing protein -
  U0450_RS06655 - 1316530..1317303 (+) 774 WP_000575633.1 TatD family hydrolase -
  U0450_RS06660 rnmV 1317303..1317863 (+) 561 WP_000660009.1 ribonuclease M5 -
  U0450_RS06665 comR 1317935..1318834 (+) 900 WP_050115346.1 helix-turn-helix transcriptional regulator Regulator
  U0450_RS06670 - 1319154..1319446 (+) 293 Protein_1289 lactococcin 972 family bacteriocin -
  U0450_RS06675 - 1319523..1321553 (+) 2031 WP_000825268.1 bacteriocin-associated integral membrane family protein -
  U0450_RS06680 - 1321555..1322196 (+) 642 WP_000565531.1 ABC transporter ATP-binding protein -
  U0450_RS06685 - 1322189..1322497 (+) 309 WP_000333257.1 hypothetical protein -
  U0450_RS06690 rsmA 1322628..1323500 (+) 873 WP_001216863.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35298.10 Da        Isoelectric Point: 4.8932

>NTDB_id=832457 U0450_RS06665 WP_050115346.1 1317935..1318834(+) (comR) [Streptococcus pneumoniae strain 15P2112]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIAHRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=832457 U0450_RS06665 WP_050115346.1 1317935..1318834(+) (comR) [Streptococcus pneumoniae strain 15P2112]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCACC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(70-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

38.144

97.324

0.371
  comR Streptococcus suis 05ZYH33

38.144

97.324

0.371
  comR Streptococcus mutans UA159

37.415

98.328

0.368
  comR Streptococcus suis D9

36.12

100

0.361