Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   U0450_RS03460 Genome accession   NZ_CP139863
Coordinates   691156..691788 (-) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P2112     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 686156..696788
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS03435 tig 687187..688470 (-) 1284 WP_000116462.1 trigger factor -
  U0450_RS03440 - 688664..689023 (-) 360 WP_000378123.1 tyrosine-type recombinase/integrase -
  U0450_RS03445 - 689325..689927 (-) 603 Protein_684 trypsin-like serine peptidase -
  U0450_RS03450 - 690386..690991 (-) 606 Protein_685 DNA alkylation repair protein -
  U0450_RS03455 - 690913..691155 (-) 243 Protein_686 DNA alkylation repair protein -
  U0450_RS03460 vraR 691156..691788 (-) 633 WP_000698433.1 response regulator transcription factor Regulator
  U0450_RS03465 - 691802..692797 (-) 996 WP_000743662.1 sensor histidine kinase -
  U0450_RS03470 liaF 692794..693492 (-) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  U0450_RS03475 fni 693570..694580 (-) 1011 WP_000210610.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  U0450_RS03480 - 694564..695571 (-) 1008 WP_050233392.1 phosphomevalonate kinase -
  U0450_RS03485 mvaD 695558..696511 (-) 954 WP_000373460.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=832411 U0450_RS03460 WP_000698433.1 691156..691788(-) (vraR) [Streptococcus pneumoniae strain 15P2112]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=832411 U0450_RS03460 WP_000698433.1 691156..691788(-) (vraR) [Streptococcus pneumoniae strain 15P2112]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41