Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   U0447_RS02335 Genome accession   NZ_CP139861
Coordinates   452064..452741 (-) Length   225 a.a.
NCBI ID   WP_000548961.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 447064..457741
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS02305 - 447225..447854 (-) 630 WP_050115971.1 NAD(P)-dependent oxidoreductase -
  U0447_RS02310 - 448093..448467 (+) 375 Protein_454 hypothetical protein -
  U0447_RS02315 - 448724..448864 (+) 141 WP_000422775.1 MazG-like protein -
  U0447_RS02320 - 448871..449047 (+) 177 WP_001837058.1 hypothetical protein -
  U0447_RS02325 thrS 449105..451048 (+) 1944 WP_000608362.1 threonine--tRNA ligase -
  U0447_RS02330 - 451097..452071 (-) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  U0447_RS02335 braR 452064..452741 (-) 678 WP_000548961.1 response regulator transcription factor Regulator
  U0447_RS02340 - 452897..453970 (+) 1074 WP_001273825.1 DUF2974 domain-containing protein -
  U0447_RS02345 - 454061..454363 (-) 303 WP_000281594.1 hypothetical protein -
  U0447_RS02350 - 454432..454869 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  U0447_RS02355 - 454945..455787 (-) 843 WP_000160958.1 metallophosphoesterase -
  U0447_RS02360 - 455899..456549 (+) 651 WP_000188498.1 metal-dependent transcriptional regulator -
  U0447_RS02365 - 456666..457287 (+) 622 Protein_465 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25950.13 Da        Isoelectric Point: 5.1362

>NTDB_id=832166 U0447_RS02335 WP_000548961.1 452064..452741(-) (braR) [Streptococcus pneumoniae strain 16H2017-2]
MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=832166 U0447_RS02335 WP_000548961.1 452064..452741(-) (braR) [Streptococcus pneumoniae strain 16H2017-2]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

34.894

100

0.364