Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   U0448_RS06230 Genome accession   NZ_CP139860
Coordinates   1209941..1210381 (-) Length   146 a.a.
NCBI ID   WP_000861973.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21011     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1204941..1215381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS06205 - 1205202..1206488 (+) 1287 WP_000278876.1 response regulator transcription factor -
  U0448_RS06210 - 1206540..1207073 (+) 534 WP_000729030.1 hypothetical protein -
  U0448_RS06215 nrdI 1207151..1207621 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  U0448_RS06220 - 1207914..1209176 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  U0448_RS06225 - 1209486..1209944 (-) 459 WP_000745059.1 DUF3021 domain-containing protein -
  U0448_RS06230 brsR 1209941..1210381 (-) 441 WP_000861973.1 LytTR family DNA-binding domain-containing protein Regulator
  U0448_RS06235 - 1210469..1210594 (-) 126 WP_001813544.1 hypothetical protein -
  U0448_RS06240 hexB 1210737..1212686 (+) 1950 WP_000018178.1 DNA mismatch repair endonuclease MutL Machinery gene
  U0448_RS06245 ribE 1213011..1213478 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  U0448_RS06250 - 1213479..1214684 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  U0448_RS06255 ribE 1214704..1215339 (-) 636 WP_000493842.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17151.84 Da        Isoelectric Point: 5.9842

>NTDB_id=832105 U0448_RS06230 WP_000861973.1 1209941..1210381(-) (brsR) [Streptococcus pneumoniae strain 21011]
MKVELQISETYEEEKLIVQAPQPTEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=832105 U0448_RS06230 WP_000861973.1 1209941..1210381(-) (brsR) [Streptococcus pneumoniae strain 21011]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363