Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   U0448_RS03970 Genome accession   NZ_CP139860
Coordinates   786234..787133 (-) Length   299 a.a.
NCBI ID   WP_081570998.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21011     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 781234..792133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS03950 rsmA 781988..782860 (-) 873 WP_001216869.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  U0448_RS03955 - 782991..783299 (-) 309 WP_000333257.1 hypothetical protein -
  U0448_RS03960 - 783292..783933 (-) 642 WP_000565531.1 ABC transporter ATP-binding protein -
  U0448_RS03965 - 783935..785965 (-) 2031 WP_000825280.1 bacteriocin-associated integral membrane family protein -
  U0448_RS03970 comR 786234..787133 (-) 900 WP_081570998.1 helix-turn-helix domain-containing protein Regulator
  U0448_RS03975 rnmV 787205..787765 (-) 561 WP_000664448.1 ribonuclease M5 -
  U0448_RS03980 - 787765..788538 (-) 774 WP_000575607.1 TatD family hydrolase -
  U0448_RS03985 - 788844..789562 (-) 719 Protein_769 DUF1542 domain-containing protein -
  U0448_RS03990 rpmH 789771..789905 (-) 135 WP_000831905.1 50S ribosomal protein L34 -
  U0448_RS03995 - 790050..791264 (-) 1215 WP_000666469.1 pyridoxal phosphate-dependent aminotransferase -
  U0448_RS04000 - 791420..791713 (-) 294 WP_000977365.1 hypothetical protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35207.03 Da        Isoelectric Point: 5.0703

>NTDB_id=832068 U0448_RS03970 WP_081570998.1 786234..787133(-) (comR) [Streptococcus pneumoniae strain 21011]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGSSQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=832068 U0448_RS03970 WP_081570998.1 786234..787133(-) (comR) [Streptococcus pneumoniae strain 21011]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGATCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(7-59)

ComR tetratricopeptide (ComR_TPR)

(70-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37.755

98.328

0.371
  comR Streptococcus suis P1/7

37.457

97.324

0.365
  comR Streptococcus suis 05ZYH33

37.457

97.324

0.365