Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R6I59_RS17935 Genome accession   NZ_CP139744
Coordinates   3394012..3394647 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis isolate FELIX_MS255     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3389012..3399647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6I59_RS17915 (R6I59_17915) yvzF 3390069..3390254 (-) 186 WP_003244599.1 YvzF family protein -
  R6I59_RS17920 (R6I59_17920) gerAA 3390372..3391820 (+) 1449 WP_009969097.1 spore germination receptor protein GerAA -
  R6I59_RS17925 (R6I59_17925) gerAB 3391789..3392886 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  R6I59_RS17930 (R6I59_17930) gerAC 3392883..3394004 (+) 1122 WP_009968146.1 spore germination receptor protein GerAC -
  R6I59_RS17935 (R6I59_17935) vraR 3394012..3394647 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  R6I59_RS17940 (R6I59_17940) liaS 3394625..3395707 (-) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  R6I59_RS17945 (R6I59_17945) liaF 3395704..3396429 (-) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  R6I59_RS17950 (R6I59_17950) liaG 3396463..3397335 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  R6I59_RS17955 (R6I59_17955) liaH 3397436..3398113 (-) 678 WP_003243047.1 stress responsive protein LiaH -
  R6I59_RS17960 (R6I59_17960) liaI 3398140..3398520 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=831295 R6I59_RS17935 WP_003243201.1 3394012..3394647(-) (vraR) [Bacillus subtilis isolate FELIX_MS255]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=831295 R6I59_RS17935 WP_003243201.1 3394012..3394647(-) (vraR) [Bacillus subtilis isolate FELIX_MS255]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408