Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   QL281_RS18785 Genome accession   NZ_CP125292
Coordinates   3529336..3529992 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis strain SRCM117797     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3524336..3534992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QL281_RS18755 (QL281_18755) oppF 3524588..3525505 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  QL281_RS18760 (QL281_18760) yjbB 3525612..3526829 (+) 1218 WP_080316915.1 MFS transporter -
  QL281_RS18765 (QL281_18765) yjbC 3526994..3527572 (+) 579 WP_144459369.1 GNAT family N-acetyltransferase -
  QL281_RS18770 (QL281_18770) spx 3527753..3528148 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  QL281_RS18775 (QL281_18775) yjbE 3528403..3529059 (-) 657 WP_003232944.1 TerC family protein -
  QL281_RS18780 (QL281_18780) - 3529229..3529369 (+) 141 WP_119122854.1 hypothetical protein -
  QL281_RS18785 (QL281_18785) mecA 3529336..3529992 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  QL281_RS18790 (QL281_18790) - 3529987..3530109 (-) 123 WP_003245684.1 hypothetical protein -
  QL281_RS18795 (QL281_18795) coiA 3530153..3531304 (+) 1152 WP_041056516.1 competence protein CoiA Machinery gene
  QL281_RS18800 (QL281_18800) pepF 3531534..3533363 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  QL281_RS18805 (QL281_18805) - 3533400..3533567 (-) 168 WP_003244944.1 hypothetical protein -
  QL281_RS18810 (QL281_18810) spxH 3533882..3534781 (-) 900 WP_041336637.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=830934 QL281_RS18785 WP_003232942.1 3529336..3529992(+) (mecA) [Bacillus subtilis strain SRCM117797]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=830934 QL281_RS18785 WP_003232942.1 3529336..3529992(+) (mecA) [Bacillus subtilis strain SRCM117797]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTTGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991