Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R8623_RS01775 Genome accession   NZ_AP026928
Coordinates   335378..336010 (+) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 330378..341010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS01750 (PC0401_03360) mvaD 330655..331608 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  R8623_RS01755 (PC0401_03370) - 331595..332602 (+) 1008 WP_024477740.1 phosphomevalonate kinase -
  R8623_RS01760 (PC0401_03380) fni 332586..333596 (+) 1011 WP_317649737.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R8623_RS01765 (PC0401_03390) liaF 333673..334371 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  R8623_RS01770 (PC0401_03400) - 334368..335364 (+) 997 Protein_346 sensor histidine kinase -
  R8623_RS01775 (PC0401_03410) vraR 335378..336010 (+) 633 WP_000698432.1 response regulator transcription factor Regulator
  R8623_RS01780 - 336085..336779 (+) 695 Protein_348 DNA alkylation repair protein -
  R8623_RS01785 (PC0401_03440) - 336929..337168 (+) 240 WP_000754501.1 hypothetical protein -
  R8623_RS01790 (PC0401_03450) cbpG 337249..338070 (+) 822 WP_001100135.1 choline-binding protein CbpG -
  R8623_RS01795 (PC0401_03460) cbpF 338089..339111 (+) 1023 Protein_351 choline-binding protein CbpF -
  R8623_RS01800 - 339239..340462 (-) 1224 Protein_352 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=83014 R8623_RS01775 WP_000698432.1 335378..336010(+) (vraR) [Streptococcus pneumoniae strain PZ900700406]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=83014 R8623_RS01775 WP_000698432.1 335378..336010(+) (vraR) [Streptococcus pneumoniae strain PZ900700406]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTAGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment