Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SIS06_RS17825 Genome accession   NZ_CP139188
Coordinates   3359486..3360121 (-) Length   211 a.a.
NCBI ID   WP_283933764.1    Uniprot ID   -
Organism   Bacillus subtilis strain H17-16     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3354486..3365121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIS06_RS17805 (SIS06_17805) yvzF 3355543..3355728 (-) 186 WP_003221676.1 YvzF family protein -
  SIS06_RS17810 (SIS06_17810) gerAA 3355846..3357294 (+) 1449 WP_033884692.1 spore germination receptor protein GerAA -
  SIS06_RS17815 (SIS06_17815) gerAB 3357263..3358360 (+) 1098 WP_021480573.1 spore germination receptor protein GerAB -
  SIS06_RS17820 (SIS06_17820) gerAC 3358357..3359478 (+) 1122 WP_174222640.1 spore germination receptor protein GerAC -
  SIS06_RS17825 (SIS06_17825) vraR 3359486..3360121 (-) 636 WP_283933764.1 two-component system response regulator LiaR Regulator
  SIS06_RS17830 (SIS06_17830) liaS 3360099..3361181 (-) 1083 WP_283933765.1 two-component system sensor histidine kinase LiaS -
  SIS06_RS17835 (SIS06_17835) liaF 3361178..3361903 (-) 726 WP_003228510.1 LiaRS two-component regulatory system accessory protein LiaF -
  SIS06_RS17840 (SIS06_17840) liaG 3361937..3362809 (-) 873 WP_120028557.1 DUF4097 domain-containing protein -
  SIS06_RS17845 (SIS06_17845) liaH 3362910..3363587 (-) 678 WP_283933766.1 stress responsive protein LiaH -
  SIS06_RS17850 (SIS06_17850) liaI 3363614..3363994 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23093.79 Da        Isoelectric Point: 5.1619

>NTDB_id=829873 SIS06_RS17825 WP_283933764.1 3359486..3360121(-) (vraR) [Bacillus subtilis strain H17-16]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIQATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGVELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=829873 SIS06_RS17825 WP_283933764.1 3359486..3360121(-) (vraR) [Bacillus subtilis strain H17-16]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTCAAGCTACAAAGCAAATTTGCCGGGAGCTTTCTGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTATTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTGACGAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGAGTGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.381

99.526

0.521
  degU Bacillus subtilis subsp. subtilis str. 168

37.668

100

0.398