Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H7679_RS08830 Genome accession   NZ_AP023392
Coordinates   1791258..1791947 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT300     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1786258..1796947
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS08805 (DAT300_17110) - 1786575..1787288 (-) 714 WP_024396096.1 NADPH-dependent oxidoreductase -
  H7679_RS08810 (DAT300_17120) dnaI 1787285..1788184 (-) 900 WP_024396095.1 primosomal protein DnaI -
  H7679_RS08815 (DAT300_17130) - 1788184..1789335 (-) 1152 WP_024396094.1 replication initiation/membrane attachment protein -
  H7679_RS08820 (DAT300_17140) nrdR 1789322..1789813 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  H7679_RS08825 (DAT300_17150) - 1789885..1791015 (-) 1131 WP_014636113.1 AI-2E family transporter -
  H7679_RS08830 (DAT300_17160) covR 1791258..1791947 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  H7679_RS08835 (DAT300_17170) gndA 1792029..1793456 (-) 1428 WP_014638518.1 NADP-dependent phosphogluconate dehydrogenase -
  H7679_RS08840 (DAT300_17180) - 1793553..1794092 (-) 540 WP_014736258.1 YceD family protein -
  H7679_RS08845 (DAT300_17190) trxB 1794102..1795019 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  H7679_RS08850 (DAT300_17200) - 1795033..1795257 (-) 225 WP_002936682.1 DUF4059 family protein -
  H7679_RS08855 (DAT300_17210) - 1795275..1796618 (-) 1344 WP_024396093.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=82962 H7679_RS08830 WP_012027645.1 1791258..1791947(-) (covR) [Streptococcus suis strain DAT300]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=82962 H7679_RS08830 WP_012027645.1 1791258..1791947(-) (covR) [Streptococcus suis strain DAT300]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAGCAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGGACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATTAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment