Detailed information NTG0829413

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SKB18_RS00330
• Genome accession: NZ_CP139163
• Coordinates: 64733..65959 (+)
• Length: 408 a.a.
• NCBI ID: WP_002934974.1
• Uniprot ID: A0A0H3MZQ3
• Organism: Streptococcus suis strain cnzyss2-311
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 59733..70959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SKB18_RS00300	-	60737..61072 (+)	336	WP_002934966.1	hypothetical protein	-
SKB18_RS00305	-	61168..62127 (+)	960	WP_012775086.1	ROK family glucokinase	-
SKB18_RS00310	-	62253..62531 (+)	279	WP_012775087.1	hypothetical protein	-
SKB18_RS00315	-	62543..62845 (+)	303	WP_012775088.1	hypothetical protein	-
SKB18_RS00320	-	62898..63737 (+)	840	WP_011922359.1	thymidylate synthase	-
SKB18_RS00325	-	64023..64535 (+)	513	WP_011922360.1	dihydrofolate reductase	-
SKB18_RS00330	clpX	64733..65959 (+)	1227	WP_002934974.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SKB18_RS00335	yihA	66015..66602 (+)	588	WP_012775089.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
SKB18_RS00340	ndk	66625..67038 (+)	414	WP_012028095.1	nucleoside-diphosphate kinase	-
SKB18_RS00345	-	67142..67813 (+)	672	WP_011922364.1	HIRAN domain-containing protein	-
SKB18_RS00350	lepA	68095..69927 (+)	1833	WP_002943192.1	translation elongation factor 4	-
SKB18_RS00355	-	69977..70159 (-)	183	WP_002934978.1	4-oxalocrotonate tautomerase	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45318.84 Da
• Isoelectric Point: 4.6382

>NTDB_id=829413 SKB18_RS00330 WP_002934974.1 64733..65959(+) (clpX) [Streptococcus suis strain cnzyss2-311]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide

• Length: 1227 bp

>NTDB_id=829413 SKB18_RS00330 WP_002934974.1 64733..65959(+) (clpX) [Streptococcus suis strain cnzyss2-311]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCAGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTAGATGAAATTGATAAGAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGTAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAAACTGGTGCTCGTGGACTTCGCTCTATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAA
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (11-47)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (311-389)

• AAA domain (Cdc48 subfamily) (AAA_2) (109-304)

3D structure

• AlphaFold DB: A0A0H3MZQ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	83.13	100	0.833
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.209	98.529	0.574