Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   H7677_RS05280 Genome accession   NZ_AP023391
Coordinates   1064039..1065265 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain DAT299     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1059039..1070265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS05250 (DAT299_09990) - 1059074..1059298 (-) 225 WP_184494383.1 hypothetical protein -
  H7677_RS05255 (DAT299_10000) - 1059360..1060667 (-) 1308 WP_172013484.1 excalibur calcium-binding domain-containing protein -
  H7677_RS05260 (DAT299_10010) - 1060802..1060984 (+) 183 WP_172013483.1 4-oxalocrotonate tautomerase -
  H7677_RS05265 (DAT299_10020) lepA 1061034..1062866 (-) 1833 WP_002943192.1 translation elongation factor 4 -
  H7677_RS05270 (DAT299_10030) ndk 1062962..1063374 (-) 413 Protein_1002 nucleoside-diphosphate kinase -
  H7677_RS05275 (DAT299_10040) yihA 1063397..1063984 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  H7677_RS05280 (DAT299_10050) clpX 1064039..1065265 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  H7677_RS05285 (DAT299_10070) - 1065463..1065975 (-) 513 WP_024405715.1 dihydrofolate reductase -
  H7677_RS05290 (DAT299_10080) - 1066246..1067085 (-) 840 WP_184492958.1 thymidylate synthase -
  H7677_RS05295 (DAT299_10090) - 1067441..1067719 (-) 279 WP_024381822.1 hypothetical protein -
  H7677_RS05300 (DAT299_10100) - 1067845..1068804 (-) 960 WP_024403091.1 ROK family glucokinase -
  H7677_RS05305 (DAT299_10110) - 1068898..1069233 (-) 336 WP_002934966.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=82901 H7677_RS05280 WP_002934974.1 1064039..1065265(-) (clpX) [Streptococcus suis strain DAT299]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=82901 H7677_RS05280 WP_002934974.1 1064039..1065265(-) (clpX) [Streptococcus suis strain DAT299]
ATGGCAGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTATAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TAAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAGAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTAGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAGGCAATTGAGCGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment