Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   H7677_RS02065 Genome accession   NZ_AP023391
Coordinates   417486..418778 (+) Length   430 a.a.
NCBI ID   WP_184493900.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT299     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 412486..423778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS02040 (DAT299_03630) - 413290..413931 (+) 642 WP_184493896.1 response regulator transcription factor -
  H7677_RS02045 (DAT299_03640) - 413981..415381 (+) 1401 WP_184493898.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  H7677_RS02050 (DAT299_03650) - 415383..415754 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  H7677_RS02055 (DAT299_03660) cysK 415781..416707 (-) 927 WP_002937015.1 cysteine synthase A -
  H7677_RS02060 (DAT299_03670) - 416797..417429 (-) 633 WP_015646510.1 YigZ family protein -
  H7677_RS02065 (DAT299_03680) comFA/cflA 417486..418778 (+) 1293 WP_184493900.1 DEAD/DEAH box helicase Machinery gene
  H7677_RS02070 (DAT299_03690) - 418771..419436 (+) 666 WP_184493902.1 ComF family protein -
  H7677_RS02075 (DAT299_03700) hpf 419513..420055 (+) 543 WP_004194117.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48758.26 Da        Isoelectric Point: 9.1743

>NTDB_id=82886 H7677_RS02065 WP_184493900.1 417486..418778(+) (comFA/cflA) [Streptococcus suis strain DAT299]
MKELENYYGRLFTKYQLTSAEREKAEKLSSVTDKNACFRCGTVFEEENKLPNDATYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGKSEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=82886 H7677_RS02065 WP_184493900.1 417486..418778(+) (comFA/cflA) [Streptococcus suis strain DAT299]
ATGAAAGAATTAGAAAATTATTACGGTAGATTATTTACCAAATACCAATTGACCTCAGCAGAGCGAGAAAAAGCAGAGAA
GCTATCCAGTGTCACAGACAAGAATGCCTGCTTTCGCTGTGGTACAGTTTTTGAAGAAGAAAACAAGTTGCCAAATGATG
CAACTTACTGTCGAGCCTGTTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAAAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGTAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTCCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGATGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGGGTCGGTAGGAGTATGGAACGTCCGACCGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(289-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.357

100

0.665
  comFA/cflA Streptococcus pneumoniae Rx1

65.661

100

0.658
  comFA/cflA Streptococcus pneumoniae D39

65.661

100

0.658
  comFA/cflA Streptococcus pneumoniae R6

65.661

100

0.658
  comFA/cflA Streptococcus pneumoniae TIGR4

65.661

100

0.658
  comFA/cflA Streptococcus mitis SK321

65.429

100

0.656
  comFA Lactococcus lactis subsp. cremoris KW2

53.186

94.884

0.505
  comFA Latilactobacillus sakei subsp. sakei 23K

37.674

100

0.377

Multiple sequence alignment