Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   SGI39_RS05060 Genome accession   NZ_CP138892
Coordinates   1064473..1066257 (+) Length   594 a.a.
NCBI ID   WP_353058872.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 1315     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1059473..1071257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGI39_RS05040 (SGI39_05040) polX 1059592..1061304 (+) 1713 WP_000161927.1 DNA polymerase/3'-5' exonuclease PolX -
  SGI39_RS05045 (SGI39_05045) mutS/mutS2 1061314..1063662 (+) 2349 WP_217654593.1 endonuclease MutS2 Machinery gene
  SGI39_RS05050 (SGI39_05050) trxA 1063835..1064149 (+) 315 WP_001018928.1 thioredoxin -
  SGI39_RS05055 (SGI39_05055) - 1064212..1064307 (-) 96 WP_001788625.1 hypothetical protein -
  SGI39_RS05060 (SGI39_05060) uvrC 1064473..1066257 (+) 1785 WP_353058872.1 excinuclease ABC subunit UvrC Machinery gene
  SGI39_RS05065 (SGI39_05065) - 1066581..1067195 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  SGI39_RS05070 (SGI39_05070) sdhA 1067247..1069013 (+) 1767 WP_000818277.1 succinate dehydrogenase flavoprotein subunit -
  SGI39_RS05075 (SGI39_05075) sdhB 1069013..1069828 (+) 816 WP_000132055.1 succinate dehydrogenase iron-sulfur subunit -
  SGI39_RS05080 (SGI39_05080) racE 1070064..1070864 (+) 801 WP_001039659.1 glutamate racemase -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68794.51 Da        Isoelectric Point: 9.7027

>NTDB_id=828841 SGI39_RS05060 WP_353058872.1 1064473..1066257(+) (uvrC) [Staphylococcus aureus strain 1315]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRHFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEM
IQSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVS
AMVTFVDGKPDKKNYRKYKIKTVKGPDDYKLMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPV
AGLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIEGIGSKRKTLLLRS
FGSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=828841 SGI39_RS05060 WP_353058872.1 1064473..1066257(+) (uvrC) [Staphylococcus aureus strain 1315]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGAGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGAGAAATACGGCATTTTGAATTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTCATTAAAAT
TACGAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGCGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAAGAATTTTATACAT
TTATTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATG
ATTCAATCTGTTGTGGACACTAAAATCGTTCAACCTGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAA
CGCTAAAGTATCTTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCTATTGAAGAACTTG
GAACACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCA
GCAATGGTTACATTTGTCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGA
TGATTACAAATTAATGAGAGAAGTAGTAAGACGCCGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAA
TAATAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTT
GCAGGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATAGTACCACTGAAGAA
AAATAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGGCAAACAC
GTCAAAAGACAGGCTTGAAATCAATCCTTGATGATATAGAGGGTATCGGTAGCAAACGTAAAACATTATTATTACGTTCA
TTCGGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAA
CCTACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(380-527)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

56.997

98.653

0.562
  uvrC Streptococcus pneumoniae TIGR4

56.997

98.653

0.562
  uvrC Streptococcus pneumoniae D39

56.997

98.653

0.562