Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QL049_RS07765 Genome accession   NZ_CP124856
Coordinates   1654427..1655056 (-) Length   209 a.a.
NCBI ID   WP_070407820.1    Uniprot ID   A0A8H9BX43
Organism   Staphylococcus pseudintermedius strain 452964 isolate human     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1649427..1660056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QL049_RS07740 (QL049_07740) - 1650603..1650806 (-) 204 WP_014613487.1 DUF1128 family protein -
  QL049_RS07745 (QL049_07745) - 1650940..1651398 (+) 459 WP_014613486.1 low molecular weight protein-tyrosine-phosphatase -
  QL049_RS07750 (QL049_07750) - 1651406..1651693 (+) 288 WP_014613485.1 YtxH domain-containing protein -
  QL049_RS07755 (QL049_07755) - 1651909..1653246 (+) 1338 WP_014613484.1 YihY/virulence factor BrkB family protein -
  QL049_RS07760 (QL049_07760) - 1653279..1653860 (+) 582 WP_015729388.1 carbonic anhydrase -
  QL049_RS07765 (QL049_07765) vraR 1654427..1655056 (-) 630 WP_070407820.1 response regulator transcription factor Regulator
  QL049_RS07770 (QL049_07770) vraS 1655046..1656089 (-) 1044 WP_014613481.1 sensor histidine kinase Regulator
  QL049_RS07775 (QL049_07775) liaF 1656086..1656787 (-) 702 WP_014613480.1 cell wall-active antibiotics response protein LiaF -
  QL049_RS07780 (QL049_07780) - 1656800..1657189 (-) 390 WP_014613479.1 hypothetical protein -
  QL049_RS07785 (QL049_07785) map 1657287..1658048 (-) 762 WP_014613478.1 type I methionyl aminopeptidase -
  QL049_RS07790 (QL049_07790) - 1658145..1659143 (+) 999 WP_014613477.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23514.19 Da        Isoelectric Point: 5.1671

>NTDB_id=828530 QL049_RS07765 WP_070407820.1 1654427..1655056(-) (vraR) [Staphylococcus pseudintermedius strain 452964 isolate human]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAITKAHELKPDLILMDLVMTDMDGVEATMQIKKDLPHIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSANDIAEAVRKTSRGESVFEAEVLVKMRNRMKQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=828530 QL049_RS07765 WP_070407820.1 1654427..1655056(-) (vraR) [Staphylococcus pseudintermedius strain 452964 isolate human]
ATGACAATTAAAGTATTATTTGTTGATGATCATGAAATGGTACGTATTGGGATTTCAAGTTATTTATCAACACAACCCGA
TATCGAAGTAGTGGGAGAAGGTGCCTCAGGTAAAGAAGCAATCACAAAAGCCCACGAATTGAAACCAGATTTAATTTTAA
TGGATTTAGTGATGACGGATATGGACGGCGTTGAAGCGACAATGCAAATTAAGAAAGATTTGCCACATATTAAAGTCGTG
ATGCTGACGAGTTATATTGAAGATAAAGAAGTGTATCGAGCGTTAGATGCCGGTGTCGATAGTTACATTTTAAAAACGAC
GAGTGCGAATGATATTGCGGAAGCTGTACGTAAAACGAGTCGTGGTGAGTCTGTGTTTGAAGCGGAAGTATTAGTGAAAA
TGCGCAATCGAATGAAGCAGCGTGCGGAGTTATATGAATTGTTGACTGAGCGCGAGATGGAAATTTTGTTGTTGATTTCA
AAAGGCTATTCGAACCAAGAGATTGCGAGTGCATCACATATTACGATTAAGACAGTGAAGACGCATGTGAGTAATATTTT
AAGTAAGCTTGAGGTGCAGGATCGTACGCAAGCGGTTATTTATGCTTTCCAACACGGCTTGATTGAGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

92.344

100

0.923
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383