Detailed information NTG0828512

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: QL049_RS00205
• Genome accession: NZ_CP124856
• Coordinates: 45708..47057 (-)
• Length: 449 a.a.
• NCBI ID: WP_214547158.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain 452964 isolate human
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	44061..47057	45708..47057	within	0

Gene organization within MGE regions

Location: 44061..47057

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QL049_RS00200 (QL049_00200)	ccrB	44061..45686 (-)	1626	WP_309256779.1	cassette chromosome recombinase CcrB	Machinery gene
QL049_RS00205 (QL049_00205)	ccrA	45708..47057 (-)	1350	WP_214547158.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52431.22 Da
• Isoelectric Point: 9.9946

>NTDB_id=828512 QL049_RS00205 WP_214547158.1 45708..47057(-) (ccrA) [Staphylococcus pseudintermedius strain 452964 isolate human]
MKQALGYLRQSTTKQQSLAAQKQTIKALAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQTYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKMITTHAPFGYHYH
NGTFTIDTVKAPTIKAVFNYYLQGYGYKKIAQYLEADDKFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVTRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKPNHSLRYYVCPQNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDIETKTTLNHEQLIEKLAQGKIDAETFREQTQSLHQQSKPISSISAYQIRKAFQ
NIIQQRFTLNMLYPYIDEINISKNKSLAGIYFKNEPLNIVKQTMKLSIV

Nucleotide

• Length: 1350 bp

>NTDB_id=828512 QL049_RS00205 WP_214547158.1 45708..47057(-) (ccrA) [Staphylococcus pseudintermedius strain 452964 isolate human]
ATGAAACAAGCACTAGGTTACTTACGCCAGAGCACTACAAAGCAACAATCCTTAGCAGCACAAAAACAAACCATCAAGGC
ATTAGCCGAAAAACATAATATTCAGCACATTACCTTTTATAGCGATAAACAATCAGGACGTACTGATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAGGGACAATGTGACGTATTATGTTGCTATCGTCTAAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAGCTCATGAAATTATGTCAAACGTATCATGTTCATATCTTAAGCGTTCATGATGGCTACTTCGA
CATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAAACAAGGTAAAATGATTACAACACATGCACCCTTTGGGTATCACTATCAT
AATGGTACTTTCACAATAGACACAGTAAAAGCACCAACAATAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAAATTCATTAATCGCAAGCCCTATCAAGTGCGTAATATTATCCTTA
ACCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTACCCGAACTCAGAAACAAGTCAAACGTAAGCCGTCAGAAAATCAACTCAAACAAAAAATCAA
ATGTCCCTATTGCCATTCGACACTCACAAACATGACCGTCCGAAAACCAAATCATTCATTGCGTTACTATGTCTGTCCGC
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACAAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAACCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TATAGAAACTAAAACTACACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACATCAACAATCAAAACCTATATCATCAATCAGTGCGTATCAAATTCGAAAAGCTTTCCAA
AACATCATTCAACAACGTTTCACGCTAAACATGTTGTACCCCTATATTGATGAAATTAATATTTCTAAAAATAAAAGCCT
CGCTGGCATCTATTTCAAAAACGAACCACTGAACATTGTAAAGCAGACTATGAAATTATCAATTGTATAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (4-147)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-322)

• Recombinase (Recombinase) (170-249)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus COL	95.991	100	0.96
ccrA	Staphylococcus aureus N315	74.61	100	0.746