Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QLF90_RS10550 Genome accession   NZ_CP124854
Coordinates   2101335..2101964 (-) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   W8TS97
Organism   Staphylococcus aureus strain ED86     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2096335..2106964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QLF90_RS10520 (QLF90_10520) - 2096756..2097286 (-) 531 WP_000184383.1 acyl-CoA thioesterase -
  QLF90_RS10525 (QLF90_10525) - 2097451..2098565 (-) 1115 Protein_2037 aminopeptidase -
  QLF90_RS10530 (QLF90_10535) - 2098634..2098834 (-) 201 WP_000180460.1 DUF1128 family protein -
  QLF90_RS10535 (QLF90_10540) - 2098981..2099445 (+) 465 WP_000228670.1 low molecular weight protein-tyrosine-phosphatase -
  QLF90_RS10540 (QLF90_10545) - 2099452..2099727 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  QLF90_RS10545 (QLF90_10550) - 2100005..2101222 (+) 1218 WP_000037081.1 YihY/virulence factor BrkB family protein -
  QLF90_RS10550 (QLF90_10555) vraR 2101335..2101964 (-) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  QLF90_RS10555 (QLF90_10560) vraS 2101954..2102997 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  QLF90_RS10560 (QLF90_10565) liaF 2102994..2103695 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  QLF90_RS10565 (QLF90_10570) - 2103710..2104096 (-) 387 WP_001110178.1 hypothetical protein -
  QLF90_RS10570 (QLF90_10575) map 2104313..2105071 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  QLF90_RS10575 (QLF90_10580) - 2105276..2105449 (-) 174 WP_001791533.1 hypothetical protein -
  QLF90_RS10580 (QLF90_10585) - 2105771..2106757 (+) 987 WP_001014423.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=828483 QLF90_RS10550 WP_000153535.1 2101335..2101964(-) (vraR) [Staphylococcus aureus strain ED86]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=828483 QLF90_RS10550 WP_000153535.1 2101335..2101964(-) (vraR) [Staphylococcus aureus strain ED86]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATATTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8TS97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373