Detailed information
Bioinformatically predicted
Overview
| Name | comEA | Type | Machinery gene |
| Locus tag | QLF90_RS06860 | Genome accession | NZ_CP124854 |
| Coordinates | 1399663..1400349 (+) | Length | 228 a.a. |
| NCBI ID | WP_001794049.1 | Uniprot ID | A0A0E1X4U4 |
| Organism | Staphylococcus aureus strain ED86 | ||
| Function | dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1350551..1404139 | 1399663..1400349 | within | 0 |
Gene organization within MGE regions
Location: 1350551..1404139
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QLF90_RS06460 (QLF90_06465) | - | 1351920..1352549 (+) | 630 | Protein_1263 | exotoxin OB-fold domain-containing protein | - |
| QLF90_RS06465 (QLF90_06470) | - | 1352634..1353839 (-) | 1206 | WP_000264747.1 | tyrosine-type recombinase/integrase | - |
| QLF90_RS06470 (QLF90_06475) | - | 1354238..1354588 (+) | 351 | WP_223223779.1 | hypothetical protein | - |
| QLF90_RS06475 (QLF90_06480) | - | 1354734..1354916 (-) | 183 | WP_000705240.1 | hypothetical protein | - |
| QLF90_RS06480 (QLF90_06485) | - | 1354986..1355717 (-) | 732 | WP_410530147.1 | S24 family peptidase | - |
| QLF90_RS06485 (QLF90_06490) | - | 1355869..1356081 (+) | 213 | WP_000213811.1 | helix-turn-helix transcriptional regulator | - |
| QLF90_RS06490 (QLF90_06495) | - | 1356129..1356389 (+) | 261 | WP_000435341.1 | transcriptional regulator | - |
| QLF90_RS06495 (QLF90_06500) | - | 1356413..1356952 (-) | 540 | WP_000351243.1 | hypothetical protein | - |
| QLF90_RS06500 (QLF90_06505) | - | 1357009..1357200 (+) | 192 | WP_000389905.1 | hypothetical protein | - |
| QLF90_RS06505 (QLF90_06510) | - | 1357202..1357429 (-) | 228 | WP_000801108.1 | hypothetical protein | - |
| QLF90_RS06510 (QLF90_06515) | - | 1357485..1357811 (+) | 327 | WP_238510987.1 | hypothetical protein | - |
| QLF90_RS06515 (QLF90_06520) | - | 1357808..1357907 (+) | 100 | Protein_1274 | hypothetical protein | - |
| QLF90_RS06520 (QLF90_06525) | - | 1358056..1358319 (+) | 264 | WP_001124198.1 | helix-turn-helix domain-containing protein | - |
| QLF90_RS06525 (QLF90_06530) | - | 1358331..1358492 (+) | 162 | WP_001285962.1 | DUF1270 domain-containing protein | - |
| QLF90_RS06530 (QLF90_06535) | - | 1358585..1358914 (+) | 330 | WP_000829611.1 | hypothetical protein | - |
| QLF90_RS06535 (QLF90_06540) | - | 1358895..1359155 (+) | 261 | WP_001667298.1 | DUF1108 family protein | - |
| QLF90_RS06540 (QLF90_06545) | - | 1359170..1359649 (+) | 480 | WP_000002516.1 | siphovirus Gp157 family protein | - |
| QLF90_RS06545 (QLF90_06550) | - | 1359649..1360422 (+) | 774 | WP_031918489.1 | AAA family ATPase | - |
| QLF90_RS06550 (QLF90_06555) | - | 1360453..1361007 (+) | 555 | WP_031918488.1 | single-stranded DNA-binding protein | - |
| QLF90_RS06555 (QLF90_06560) | - | 1361020..1361691 (+) | 672 | WP_001199416.1 | putative HNHc nuclease | - |
| QLF90_RS06560 (QLF90_06565) | - | 1361688..1361837 (+) | 150 | WP_020808005.1 | hypothetical protein | - |
| QLF90_RS06565 (QLF90_06570) | - | 1361830..1362111 (-) | 282 | WP_000414755.1 | hypothetical protein | - |
| QLF90_RS06570 (QLF90_06575) | - | 1362177..1362947 (+) | 771 | WP_020808006.1 | conserved phage C-terminal domain-containing protein | - |
| QLF90_RS06575 (QLF90_06580) | - | 1362957..1363736 (+) | 780 | WP_031895056.1 | ATP-binding protein | - |
| QLF90_RS06580 (QLF90_06585) | - | 1363730..1363891 (+) | 162 | WP_000237154.1 | hypothetical protein | - |
| QLF90_RS06585 (QLF90_06590) | - | 1363905..1364125 (+) | 221 | Protein_1288 | DUF3269 family protein | - |
| QLF90_RS06590 (QLF90_06595) | - | 1364136..1364540 (+) | 405 | WP_031895072.1 | DUF1064 domain-containing protein | - |
| QLF90_RS06595 (QLF90_06600) | - | 1364545..1364733 (+) | 189 | WP_020808085.1 | DUF3113 family protein | - |
| QLF90_RS06600 (QLF90_06605) | - | 1364734..1365093 (+) | 360 | WP_061390773.1 | SA1788 family PVL leukocidin-associated protein | - |
| QLF90_RS06605 (QLF90_06610) | - | 1365094..1365342 (+) | 249 | WP_061650588.1 | SAV1978 family virulence-associated passenger protein | - |
| QLF90_RS06610 (QLF90_06615) | - | 1365357..1365749 (+) | 393 | WP_001062709.1 | hypothetical protein | - |
| QLF90_RS06615 (QLF90_06620) | - | 1365746..1365937 (+) | 192 | WP_000983947.1 | hypothetical protein | - |
| QLF90_RS06620 (QLF90_06625) | - | 1365937..1366404 (+) | 468 | WP_410530148.1 | acetyltransferase | - |
| QLF90_RS06625 (QLF90_06630) | - | 1366361..1366615 (+) | 255 | WP_001614120.1 | DUF1024 family protein | - |
| QLF90_RS06630 (QLF90_06635) | - | 1366602..1366772 (+) | 171 | WP_000714406.1 | hypothetical protein | - |
| QLF90_RS06635 (QLF90_06640) | - | 1366765..1367301 (+) | 537 | WP_410530149.1 | dUTP diphosphatase | - |
| QLF90_RS06640 (QLF90_06645) | - | 1367338..1367583 (+) | 246 | WP_001282074.1 | hypothetical protein | - |
| QLF90_RS06645 (QLF90_06650) | - | 1367580..1367768 (+) | 189 | WP_208151685.1 | DUF1381 domain-containing protein | - |
| QLF90_RS06650 (QLF90_06655) | - | 1367743..1367943 (+) | 201 | WP_001125015.1 | hypothetical protein | - |
| QLF90_RS06655 (QLF90_06660) | rinB | 1367946..1368095 (+) | 150 | WP_000237868.1 | transcriptional activator RinB | - |
| QLF90_RS06660 (QLF90_06665) | - | 1368095..1368295 (+) | 201 | WP_000265041.1 | DUF1514 family protein | - |
| QLF90_RS06665 (QLF90_06670) | - | 1368318..1368779 (+) | 462 | WP_002955176.1 | hypothetical protein | - |
| QLF90_RS06670 (QLF90_06675) | - | 1368894..1369346 (+) | 453 | WP_000406186.1 | nucleoside triphosphate pyrophosphohydrolase family protein | - |
| QLF90_RS06675 (QLF90_06680) | - | 1369353..1369718 (+) | 366 | WP_000026170.1 | HNH endonuclease | - |
| QLF90_RS06680 (QLF90_06685) | - | 1369812..1370282 (+) | 471 | WP_000919030.1 | phage terminase small subunit P27 family | - |
| QLF90_RS06685 (QLF90_06690) | - | 1370282..1371976 (+) | 1695 | WP_000568449.1 | terminase large subunit | - |
| QLF90_RS06690 (QLF90_06695) | - | 1371990..1372193 (+) | 204 | WP_001052526.1 | hypothetical protein | - |
| QLF90_RS06695 (QLF90_06700) | - | 1372196..1373452 (+) | 1257 | WP_000511070.1 | phage portal protein | - |
| QLF90_RS06700 (QLF90_06705) | - | 1373871..1374455 (+) | 585 | WP_025173991.1 | HK97 family phage prohead protease | - |
| QLF90_RS06705 (QLF90_06710) | - | 1374542..1375777 (+) | 1236 | WP_000849953.1 | phage major capsid protein | - |
| QLF90_RS06710 (QLF90_06715) | - | 1375814..1375972 (+) | 159 | WP_001240639.1 | hypothetical protein | - |
| QLF90_RS06715 (QLF90_06720) | - | 1375981..1376313 (+) | 333 | WP_001177664.1 | head-tail connector protein | - |
| QLF90_RS06720 (QLF90_06725) | - | 1376303..1376635 (+) | 333 | WP_000671501.1 | head-tail adaptor protein | - |
| QLF90_RS06725 (QLF90_06730) | - | 1376635..1377012 (+) | 378 | WP_000501001.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| QLF90_RS06730 (QLF90_06735) | - | 1377009..1377389 (+) | 381 | WP_000608369.1 | hypothetical protein | - |
| QLF90_RS06735 (QLF90_06740) | - | 1377390..1378343 (+) | 954 | WP_000570645.1 | major tail protein | - |
| QLF90_RS06740 (QLF90_06745) | gpG | 1378408..1378854 (+) | 447 | WP_000442604.1 | phage tail assembly chaperone G | - |
| QLF90_RS06745 (QLF90_06750) | gpGT | 1378914..1379036 (+) | 123 | WP_000571956.1 | phage tail assembly chaperone GT | - |
| QLF90_RS06750 (QLF90_06755) | - | 1379092..1383741 (+) | 4650 | WP_410530150.1 | phage tail tape measure protein | - |
| QLF90_RS06755 (QLF90_06760) | - | 1383741..1385231 (+) | 1491 | WP_160198983.1 | phage distal tail protein | - |
| QLF90_RS06760 (QLF90_06765) | - | 1385247..1389032 (+) | 3786 | WP_410530151.1 | phage tail spike protein | - |
| QLF90_RS06765 (QLF90_06770) | - | 1389022..1389165 (+) | 144 | WP_031783159.1 | hypothetical protein | - |
| QLF90_RS06770 (QLF90_06775) | - | 1389221..1389508 (+) | 288 | WP_001040254.1 | hypothetical protein | - |
| QLF90_RS06775 (QLF90_06780) | - | 1389566..1389862 (+) | 297 | WP_000539688.1 | DUF2951 domain-containing protein | - |
| QLF90_RS06780 (QLF90_06785) | pepG1 | 1390054..1390188 (+) | 135 | WP_000226108.1 | type I toxin-antitoxin system toxin PepG1 | - |
| QLF90_RS06785 (QLF90_06790) | - | 1390241..1390348 (-) | 108 | WP_031790389.1 | hypothetical protein | - |
| QLF90_RS06790 (QLF90_06795) | - | 1390400..1390654 (+) | 255 | WP_000611512.1 | phage holin | - |
| QLF90_RS06795 (QLF90_06800) | - | 1390666..1391421 (+) | 756 | WP_000861038.1 | CHAP domain-containing protein | - |
| QLF90_RS06800 (QLF90_06805) | - | 1391799..1392635 (+) | 837 | WP_000675478.1 | hypothetical protein | - |
| QLF90_RS06805 (QLF90_06810) | - | 1393031..1393171 (+) | 141 | Protein_1332 | exotoxin | - |
| QLF90_RS06810 (QLF90_06815) | - | 1393373..1393642 (-) | 270 | WP_000829750.1 | hypothetical protein | - |
| QLF90_RS06815 (QLF90_06820) | mtnN | 1393956..1394642 (+) | 687 | WP_000579273.1 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | - |
| QLF90_RS06820 (QLF90_06825) | - | 1394662..1395189 (+) | 528 | WP_000524902.1 | YqeG family HAD IIIA-type phosphatase | - |
| QLF90_RS06825 (QLF90_06830) | yqeH | 1395190..1396290 (+) | 1101 | WP_001280134.1 | ribosome biogenesis GTPase YqeH | - |
| QLF90_RS06830 (QLF90_06835) | aroE | 1396304..1397110 (+) | 807 | WP_000666750.1 | shikimate dehydrogenase | - |
| QLF90_RS06835 (QLF90_06840) | yhbY | 1397114..1397404 (+) | 291 | WP_000955232.1 | ribosome assembly RNA-binding protein YhbY | - |
| QLF90_RS06840 (QLF90_06845) | nadD | 1397407..1397976 (+) | 570 | WP_000822938.1 | nicotinate (nicotinamide) nucleotide adenylyltransferase | - |
| QLF90_RS06845 (QLF90_06850) | yqeK | 1397966..1398550 (+) | 585 | WP_001019324.1 | bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK | - |
| QLF90_RS06850 (QLF90_06855) | rsfS | 1398551..1398904 (+) | 354 | WP_001088020.1 | ribosome silencing factor | - |
| QLF90_RS06855 (QLF90_06860) | - | 1398907..1399623 (+) | 717 | WP_000084835.1 | class I SAM-dependent DNA methyltransferase | - |
| QLF90_RS06860 (QLF90_06865) | comEA | 1399663..1400349 (+) | 687 | WP_001794049.1 | ComEA family DNA-binding protein | Machinery gene |
| QLF90_RS06865 (QLF90_06870) | - | 1400441..1400902 (+) | 462 | WP_000439692.1 | ComE operon protein 2 | - |
| QLF90_RS06870 (QLF90_06875) | comEC | 1400907..1403108 (+) | 2202 | WP_000967506.1 | DNA internalization-related competence protein ComEC/Rec2 | Machinery gene |
| QLF90_RS06875 (QLF90_06880) | holA | 1403165..1404139 (+) | 975 | WP_001282570.1 | DNA polymerase III subunit delta | - |
Sequence
Protein
Download Length: 228 a.a. Molecular weight: 25766.38 Da Isoelectric Point: 9.3383
>NTDB_id=828467 QLF90_RS06860 WP_001794049.1 1399663..1400349(+) (comEA) [Staphylococcus aureus strain ED86]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT
Nucleotide
Download Length: 687 bp
>NTDB_id=828467 QLF90_RS06860 WP_001794049.1 1399663..1400349(+) (comEA) [Staphylococcus aureus strain ED86]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comEA | Staphylococcus aureus MW2 |
95.595 |
99.561 |
0.952 |
| comEA | Staphylococcus aureus N315 |
95.595 |
99.561 |
0.952 |