Detailed information NTG0082845

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: R8559_RS09685
• Genome accession: NZ_AP026926
• Coordinates: 1862493..1863392 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904865.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700119
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1857493..1868392

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8559_RS09660 (PC0116_18980)	rsmA	1857829..1858701 (-)	873	WP_219599541.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
R8559_RS09665 (PC0116_18990)	-	1858832..1859140 (-)	309	WP_000333257.1	hypothetical protein	-
R8559_RS09670 (PC0116_19000)	-	1859133..1859774 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
R8559_RS09675 (PC0116_19010)	-	1859776..1861806 (-)	2031	WP_000825270.1	bacteriocin-associated integral membrane family protein	-
R8559_RS09680 (PC0116_19020)	-	1861883..1862179 (-)	297	WP_000815393.1	lactococcin 972 family bacteriocin	-
R8559_RS09685 (PC0116_19030)	comR	1862493..1863392 (-)	900	WP_000904865.1	helix-turn-helix domain-containing protein	Regulator
R8559_RS09690 (PC0116_19040)	rnmV	1863464..1864024 (-)	561	WP_000664448.1	ribonuclease M5	-
R8559_RS09695 (PC0116_19050)	-	1864024..1864797 (-)	774	WP_000575635.1	TatD family hydrolase	-
R8559_RS09700 (PC0116_19060)	-	1865102..1866079 (-)	978	Protein_1902	DUF1542 domain-containing protein	-
R8559_RS09705 (PC0116_19070)	rpmH	1866285..1866419 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
R8559_RS09710 (PC0116_19080)	-	1866564..1867778 (-)	1215	WP_000666465.1	pyridoxal phosphate-dependent aminotransferase	-
R8559_RS09715 (PC0116_19090)	-	1867934..1868227 (-)	294	WP_000977364.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35175.08 Da
• Isoelectric Point: 5.2018

>NTDB_id=82845 R8559_RS09685 WP_000904865.1 1862493..1863392(-) (comR) [Streptococcus pneumoniae strain PZ900700119]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=82845 R8559_RS09685 WP_000904865.1 1862493..1863392(-) (comR) [Streptococcus pneumoniae strain PZ900700119]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

• Helix-turn-helix (HTH_3) (7-59)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	38.095	98.328	0.375
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368