Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   H7675_RS05710 Genome accession   NZ_AP023389
Coordinates   1128628..1129857 (-) Length   409 a.a.
NCBI ID   WP_031488352.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain KUN-0012590     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1123628..1134857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7675_RS05690 (KUN2590_10770) rpiA 1123910..1124593 (-) 684 WP_002984936.1 ribose-5-phosphate isomerase RpiA -
  H7675_RS05695 (KUN2590_10780) - 1124971..1127070 (+) 2100 WP_031488351.1 AAA family ATPase -
  H7675_RS05700 (KUN2590_10790) - 1127128..1127871 (-) 744 WP_002984942.1 hypothetical protein -
  H7675_RS05705 (KUN2590_10800) yihA 1128019..1128618 (-) 600 WP_002990160.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  H7675_RS05710 (KUN2590_10810) clpX 1128628..1129857 (-) 1230 WP_031488352.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  H7675_RS05715 (KUN2590_10820) - 1129987..1130157 (-) 171 WP_002990165.1 hypothetical protein -
  H7675_RS05720 (KUN2590_10830) - 1130177..1130674 (-) 498 WP_111711413.1 dihydrofolate reductase -
  H7675_RS05725 (KUN2590_10840) - 1130754..1131593 (-) 840 WP_011017679.1 thymidylate synthase -
  H7675_RS05730 (KUN2590_10850) - 1131802..1132977 (+) 1176 WP_031488354.1 hydroxymethylglutaryl-CoA synthase -
  H7675_RS05735 (KUN2590_10860) - 1132964..1134241 (+) 1278 WP_010922170.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 44991.48 Da        Isoelectric Point: 4.6184

>NTDB_id=82794 H7675_RS05710 WP_031488352.1 1128628..1129857(-) (clpX) [Streptococcus pyogenes strain KUN-0012590]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIKI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=82794 H7675_RS05710 WP_031488352.1 1128628..1129857(-) (clpX) [Streptococcus pyogenes strain KUN-0012590]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGTCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTTTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTAAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.242

100

0.892
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.603

98.044

0.575

Multiple sequence alignment