Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   R8559_RS03155 Genome accession   NZ_AP026926
Coordinates   592899..593555 (+) Length   218 a.a.
NCBI ID   WP_000697959.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700119     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 587899..598555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8559_RS03125 (PC0116_06150) - 588185..588550 (+) 366 WP_001067073.1 hypothetical protein -
  R8559_RS03130 (PC0116_06160) - 588692..588862 (+) 171 Protein_617 group II intron maturase-specific domain-containing protein -
  R8559_RS03135 (PC0116_06170) - 589219..590496 (+) 1278 WP_001068293.1 ABC transporter permease -
  R8559_RS03140 (PC0116_06180) vex2 590509..591156 (+) 648 WP_000173731.1 ABC transporter ATP-binding subunit Vex2 -
  R8559_RS03145 (PC0116_06190) vex3 591208..592587 (+) 1380 WP_000902984.1 ABC transporter permease subunit Vex3 -
  R8559_RS03150 pep27 592767..592850 (+) 84 WP_199862660.1 putative autolysis signal peptide Pep27 -
  R8559_RS03155 (PC0116_06200) ciaR 592899..593555 (+) 657 WP_000697959.1 response regulator transcription factor VncR Regulator
  R8559_RS03160 (PC0116_06210) vncS 593552..594880 (+) 1329 WP_000831372.1 sensor histidine kinase VncS -
  R8559_RS03165 (PC0116_06220) - 595021..595902 (+) 882 WP_001019003.1 class II fructose-bisphosphate aldolase -
  R8559_RS03170 (PC0116_06230) - 596223..597413 (-) 1191 WP_000835815.1 ferric reductase-like transmembrane domain-containing protein -
  R8559_RS03175 (PC0116_06240) - 597557..598216 (-) 660 WP_000443840.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25000.70 Da        Isoelectric Point: 4.3898

>NTDB_id=82779 R8559_RS03155 WP_000697959.1 592899..593555(+) (ciaR) [Streptococcus pneumoniae strain PZ900700119]
MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYEVALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAF
QDEEYKMSAFASLADGYLEKPFSLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCIFTVRNVGYKLERK

Nucleotide


Download         Length: 657 bp        

>NTDB_id=82779 R8559_RS03155 WP_000697959.1 592899..593555(+) (ciaR) [Streptococcus pneumoniae strain PZ900700119]
ATGAAAATTTTAATTGTAGAAGATGAAGAGATGATCCGTGAGGGGGTCAGTGATTATTTGACGGATTGTGGCTATGAAAC
TATTGAGGCAGCGGACGGTCAGGAAGCTCTGGAGCAATTTTCTAGCTATGAGGTGGCCCTGGTTTTACTGGATATCCAGA
TGCCCAAGCTTAACGGCTTAGAAGTCCTAGCTGAGATTCGTAAAACCAGTCAGGTTCCTGTCTTGATGTTGACAGCTTTT
CAGGATGAGGAATACAAGATGAGTGCCTTTGCCTCTTTGGCAGATGGCTATCTGGAAAAACCTTTCTCCCTCTCCCTCTT
AAAAGTGAGGGTGGACGCGATTTTCAAGCGCTACTACGATACAGGACGAATCTTTTCTTACAAGGATACCAAGGTGGACT
TTGAAAGCTACAGTGCAAGCCTCGCAGGTCAAGAAGTGCCTATCAATGCCAAAGAGTTGGAAATTCTGGACTATCTAGTG
AAAAATGAAGGCCGGGCCTTGACTCGGTCTCAGATTATCGATGCCGTCTGGAAAGCGACAGATGAGGTTCCCTTTGACCG
TGTTATTGATGTTTATATCAAGGAATTGCGGAAAAAGCTAGACTTGGATTGTATCTTCACTGTGCGCAATGTTGGTTATA
AATTGGAGCGAAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(143-215)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

34.956

100

0.362
  micA Streptococcus pneumoniae Cp1015

34.802

100

0.362

Multiple sequence alignment