Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   KUN2590_RS09700 Genome accession   NZ_AP023387
Coordinates   54246..54344 (+) Length   32 a.a.
NCBI ID   WP_020833188.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NIH34     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 49246..59344
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KUN2590_RS00320 (SPNIH34_00290) - 50112..51452 (+) 1341 WP_002986685.1 hypothetical protein -
  KUN2590_RS00325 (SPNIH34_00300) purB 51821..53113 (+) 1293 WP_011054098.1 adenylosuccinate lyase -
  KUN2590_RS00330 (SPNIH34_00310) comR 53244..54155 (+) 912 WP_011054099.1 helix-turn-helix domain-containing protein Regulator
  KUN2590_RS09700 comS 54246..54344 (+) 99 WP_020833188.1 quorum-sensing system DWW-type pheromone Regulator
  KUN2590_RS00335 (SPNIH34_00320) ruvB 54375..55373 (+) 999 WP_011054100.1 Holliday junction branch migration DNA helicase RuvB -
  KUN2590_RS00340 (SPNIH34_00330) - 55511..55948 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  KUN2590_RS00345 (SPNIH34_00340) - 55971..56372 (+) 402 WP_011017240.1 MORN repeat-containing protein -
  KUN2590_RS00350 (SPNIH34_00350) - 56369..58144 (+) 1776 WP_011054101.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 32 a.a.        Molecular weight: 3758.63 Da        Isoelectric Point: 10.7919

>NTDB_id=82706 KUN2590_RS09700 WP_020833188.1 54246..54344(+) (comS) [Streptococcus pyogenes strain NIH34]
MLKKVKPFLLLAAVVAFKVARVMHEFDWWNLG

Nucleotide


Download         Length: 99 bp        

>NTDB_id=82706 KUN2590_RS09700 WP_020833188.1 54246..54344(+) (comS) [Streptococcus pyogenes strain NIH34]
ATGTTAAAAAAAGTTAAGCCATTTTTACTATTAGCCGCAGTAGTTGCATTTAAAGTTGCTCGTGTAATGCATGAATTTGA
TTGGTGGAATCTTGGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

100

100

1
  comS Streptococcus pyogenes MGAS8232

45.161

96.875

0.437

Multiple sequence alignment