Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R8507_RS01860 Genome accession   NZ_AP026925
Coordinates   350125..350757 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain PZ900700097     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 345125..355757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8507_RS01835 (PC0094_03530) mvaD 345402..346355 (+) 954 WP_000373461.1 diphosphomevalonate decarboxylase -
  R8507_RS01840 (PC0094_03540) - 346342..347349 (+) 1008 WP_000562412.1 phosphomevalonate kinase -
  R8507_RS01845 (PC0094_03550) fni 347333..348343 (+) 1011 WP_044812571.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R8507_RS01850 (PC0094_03560) liaF 348421..349119 (+) 699 WP_001224640.1 cell wall-active antibiotics response protein LiaF -
  R8507_RS01855 (PC0094_03570) - 349116..350111 (+) 996 WP_000743684.1 sensor histidine kinase -
  R8507_RS01860 (PC0094_03580) vraR 350125..350757 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  R8507_RS01865 - 350833..351526 (+) 694 Protein_365 DNA alkylation repair protein -
  R8507_RS01870 (PC0094_03610) - 351676..351915 (+) 240 WP_000754501.1 hypothetical protein -
  R8507_RS01875 (PC0094_03620) cbpG 351996..352817 (+) 822 WP_001100142.1 choline-binding protein CbpG -
  R8507_RS01880 (PC0094_03630) cbpF 352836..353858 (+) 1023 WP_000765210.1 choline-binding protein CbpF -
  R8507_RS01885 - 353986..355132 (-) 1147 Protein_369 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=82649 R8507_RS01860 WP_000698434.1 350125..350757(+) (vraR) [Streptococcus pneumoniae strain PZ900700097]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=82649 R8507_RS01860 WP_000698434.1 350125..350757(+) (vraR) [Streptococcus pneumoniae strain PZ900700097]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGAATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment