Detailed information NTG0827015

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: P7I78_RS21880
• Genome accession: NZ_CP124646
• Coordinates: 4671418..4673643 (-)
• Length: 741 a.a.
• NCBI ID: WP_003138588.1
• Uniprot ID: A0A0H2ZCX3
• Organism: Pseudomonas aeruginosa strain 2020CK-00185
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 4666418..4678643

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P7I78_RS21845 (P7I78_21845)	murB	4666808..4667827 (-)	1020	WP_003119807.1	UDP-N-acetylmuramate dehydrogenase	-
P7I78_RS21850 (P7I78_21850)	-	4667824..4668288 (-)	465	WP_003138590.1	low molecular weight protein-tyrosine-phosphatase	-
P7I78_RS21855 (P7I78_21855)	kdsB	4668288..4669052 (-)	765	WP_003130694.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
P7I78_RS21860 (P7I78_21860)	-	4669052..4669237 (-)	186	WP_003091157.1	Trm112 family protein	-
P7I78_RS21865 (P7I78_21865)	lpxK	4669275..4670273 (-)	999	WP_003091159.1	tetraacyldisaccharide 4'-kinase	-
P7I78_RS21870 (P7I78_21870)	-	4670273..4670713 (-)	441	WP_003091161.1	biopolymer transporter ExbD	-
P7I78_RS21875 (P7I78_21875)	exbB	4670710..4671345 (-)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
P7I78_RS21880 (P7I78_21880)	comA	4671418..4673643 (-)	2226	WP_003138588.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
P7I78_RS21885 (P7I78_21885)	-	4673774..4674307 (+)	534	WP_003091165.1	DUF2062 domain-containing protein	-
P7I78_RS21890 (P7I78_21890)	-	4674395..4675639 (-)	1245	WP_003105198.1	lipoprotein-releasing ABC transporter permease subunit	-
P7I78_RS21895 (P7I78_21895)	lolD	4675709..4676392 (-)	684	WP_003109474.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
P7I78_RS21900 (P7I78_21900)	-	4676385..4677635 (-)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
P7I78_RS21905 (P7I78_21905)	-	4677738..4678337 (+)	600	WP_016254241.1	PilZ domain-containing protein	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79970.55 Da
• Isoelectric Point: 10.4652

>NTDB_id=827015 P7I78_RS21880 WP_003138588.1 4671418..4673643(-) (comA) [Pseudomonas aeruginosa strain 2020CK-00185]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GKVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHALLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPGWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
FLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=827015 P7I78_RS21880 WP_003138588.1 4671418..4673643(-) (comA) [Pseudomonas aeruginosa strain 2020CK-00185]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCAAGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCGGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGTGCTTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTATGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCGTTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGGGAGCATGCCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGGTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCGCAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGACCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
TTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A0H2ZCX3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.946	97.301	0.574
comA	Ralstonia pseudosolanacearum GMI1000	35.611	100	0.366