Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   QA539_RS06190 Genome accession   NZ_CP124591
Coordinates   1214570..1215541 (-) Length   323 a.a.
NCBI ID   WP_219492120.1    Uniprot ID   -
Organism   Macrococcus sp. CCM 8659     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1209570..1220541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA539_RS06155 (QA539_06135) gcvT 1210267..1211352 (-) 1086 WP_219494831.1 glycine cleavage system aminomethyltransferase GcvT -
  QA539_RS06160 (QA539_06140) - 1211490..1211996 (-) 507 WP_219491935.1 shikimate kinase -
  QA539_RS06165 (QA539_06145) comGF 1212157..1212609 (-) 453 WP_219491938.1 competence type IV pilus minor pilin ComGF -
  QA539_RS06170 (QA539_06150) - 1212554..1212796 (-) 243 WP_419894979.1 hypothetical protein -
  QA539_RS06175 (QA539_06155) comGD 1212783..1213208 (-) 426 WP_101037039.1 competence type IV pilus minor pilin ComGD -
  QA539_RS06180 (QA539_06160) comGC 1213201..1213524 (-) 324 WP_283722000.1 competence type IV pilus major pilin ComGC Machinery gene
  QA539_RS06185 (QA539_06165) comGB 1213546..1214619 (-) 1074 WP_419894980.1 competence type IV pilus assembly protein ComGB -
  QA539_RS06190 (QA539_06170) comGA 1214570..1215541 (-) 972 WP_219492120.1 competence type IV pilus ATPase ComGA Machinery gene
  QA539_RS06195 (QA539_06175) - 1215753..1216001 (+) 249 WP_041636023.1 DUF2626 domain-containing protein -
  QA539_RS06200 (QA539_06180) - 1216029..1216649 (-) 621 WP_219492123.1 MBL fold metallo-hydrolase -
  QA539_RS06205 (QA539_06185) - 1216739..1216978 (+) 240 WP_219492126.1 DUF2759 domain-containing protein -
  QA539_RS06210 (QA539_06190) - 1217005..1217316 (-) 312 WP_086038848.1 MTH1187 family thiamine-binding protein -
  QA539_RS06215 (QA539_06195) - 1217316..1218284 (-) 969 WP_419894981.1 ROK family glucokinase -
  QA539_RS06220 (QA539_06200) - 1218281..1218472 (-) 192 WP_133445012.1 YqgQ family protein -
  QA539_RS06225 (QA539_06205) - 1218477..1219925 (-) 1449 WP_419894982.1 rhomboid family intramembrane serine protease -
  QA539_RS06230 (QA539_06210) - 1219901..1220455 (-) 555 WP_211517715.1 5-formyltetrahydrofolate cyclo-ligase -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 37050.64 Da        Isoelectric Point: 6.4160

>NTDB_id=826527 QA539_RS06190 WP_219492120.1 1214570..1215541(-) (comGA) [Macrococcus sp. CCM 8659]
MERLFNEIIEQAILQSASDIHFIPGDKSISIKFRIQGDIEDYSDIDDILFRKLLSYIKFTAHLDVSEKNKAQSGIIHFNL
NNLRYNIRASTLPRSLGDEACVLRIIRQSFIDEYQTDDQILFNQMKKSSGIIIISGPTGSGKSTLMYQLVHFAKNTLKRQ
VISIEDPVEQHIDGIIQVNVNEKAEITYQTAIKAILRCDPDIIMLGEIRDSVVAQQVINAGLSGHLVLTTLHANDCIGAL
FRLKEMGINAVDLYQSINLIINQRLVKRIDGKERVLAYEFLTKKDIEKYLKDKHINYRTLADIFKEMYETNQISQHEFEK
FDL

Nucleotide


Download         Length: 972 bp        

>NTDB_id=826527 QA539_RS06190 WP_219492120.1 1214570..1215541(-) (comGA) [Macrococcus sp. CCM 8659]
ATGGAGAGATTATTCAATGAAATAATAGAGCAGGCAATTTTACAAAGTGCATCAGATATACACTTCATTCCTGGTGATAA
AAGCATATCTATTAAATTTAGGATACAAGGTGATATTGAAGACTATAGCGACATCGACGATATATTATTTAGAAAACTAC
TTTCATATATTAAATTTACAGCACATCTTGATGTATCAGAAAAGAATAAGGCCCAGAGTGGCATAATACATTTTAACCTG
AATAACTTACGATACAATATTCGCGCATCTACTTTACCTCGGTCATTAGGTGATGAAGCATGTGTATTGAGGATTATCAG
ACAAAGTTTTATAGATGAATATCAGACAGATGATCAAATATTGTTCAATCAAATGAAAAAATCAAGCGGTATAATTATCA
TTAGTGGACCAACTGGAAGTGGTAAAAGTACATTAATGTATCAACTTGTACATTTTGCGAAGAATACATTGAAACGACAA
GTAATTTCAATAGAAGATCCTGTAGAACAGCATATTGACGGTATCATACAAGTTAATGTTAACGAAAAAGCAGAGATAAC
GTATCAAACCGCGATAAAGGCAATCCTTAGATGTGATCCAGATATCATTATGCTAGGTGAAATAAGAGATTCAGTCGTAG
CCCAGCAAGTTATCAATGCAGGGTTAAGCGGGCATTTAGTTTTAACGACATTACATGCGAATGATTGCATCGGCGCATTA
TTTCGACTTAAAGAAATGGGAATTAATGCTGTTGATCTATATCAAAGTATTAATTTAATTATCAATCAAAGACTTGTAAA
AAGAATAGATGGAAAGGAGCGTGTTTTAGCCTATGAATTTTTGACAAAAAAGGATATTGAAAAATATTTAAAGGATAAAC
ATATAAACTATAGAACGCTGGCTGACATATTTAAGGAGATGTATGAAACAAATCAGATTTCACAACATGAATTTGAAAAA
TTTGATCTATAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

49.695

100

0.505
  comGA Staphylococcus aureus N315

49.695

100

0.505
  comGA Bacillus subtilis subsp. subtilis str. 168

34.483

100

0.372