Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R8635_RS03255 Genome accession   NZ_AP026924
Coordinates   626764..627441 (+) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 621764..632441
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS03225 (PC0062_06330) - 622104..622769 (-) 666 WP_268218074.1 nicotinamide mononucleotide transporter -
  R8635_RS03230 (PC0062_06340) - 622957..623607 (-) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  R8635_RS03235 (PC0062_06350) - 623719..624561 (+) 843 WP_000160934.1 metallophosphoesterase -
  R8635_RS03240 (PC0062_06360) - 624637..625074 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  R8635_RS03245 (PC0062_06370) - 625142..625444 (+) 303 WP_000281608.1 hypothetical protein -
  R8635_RS03250 (PC0062_06380) - 625535..626608 (-) 1074 WP_001273816.1 DUF2974 domain-containing protein -
  R8635_RS03255 (PC0062_06390) braR 626764..627441 (+) 678 WP_000548991.1 response regulator transcription factor Regulator
  R8635_RS03260 (PC0062_06400) - 627434..628408 (+) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  R8635_RS03265 (PC0062_06410) thrS 628457..630400 (-) 1944 WP_050144942.1 threonine--tRNA ligase -
  R8635_RS03270 (PC0062_06420) - 630458..630634 (-) 177 WP_000166031.1 MazG-like protein -
  R8635_RS03275 (PC0062_06430) - 630641..630781 (-) 141 WP_000422775.1 MazG-like protein -
  R8635_RS03280 - 631038..631412 (-) 375 Protein_650 hypothetical protein -
  R8635_RS03285 (PC0062_06440) - 631651..632280 (+) 630 WP_001864883.1 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=82531 R8635_RS03255 WP_000548991.1 626764..627441(+) (braR) [Streptococcus pneumoniae strain PZ900700063]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=82531 R8635_RS03255 WP_000548991.1 626764..627441(+) (braR) [Streptococcus pneumoniae strain PZ900700063]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCAGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369