Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SC043_RS08045 Genome accession   NZ_CP138309
Coordinates   1581560..1582189 (-) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis strain B26     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1576560..1587189
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SC043_RS08020 (SC043_08020) - 1577491..1578735 (-) 1245 WP_010905612.1 FtsW/RodA/SpoVE family cell cycle protein -
  SC043_RS08025 (SC043_08025) - 1578955..1579560 (-) 606 WP_003131406.1 TVP38/TMEM64 family protein -
  SC043_RS08030 (SC043_08030) - 1579557..1579988 (-) 432 WP_010905611.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  SC043_RS08035 (SC043_08035) - 1579990..1580580 (-) 591 WP_003131404.1 peptidylprolyl isomerase -
  SC043_RS08040 (SC043_08040) - 1580683..1581489 (-) 807 WP_003131403.1 Cof-type HAD-IIB family hydrolase -
  SC043_RS08045 (SC043_08045) vraR 1581560..1582189 (-) 630 WP_003131402.1 response regulator transcription factor Regulator
  SC043_RS08050 (SC043_08050) - 1582217..1583215 (-) 999 WP_021214569.1 sensor histidine kinase -
  SC043_RS08055 (SC043_08055) liaF 1583212..1583841 (-) 630 WP_010905609.1 cell wall-active antibiotics response protein LiaF -
  SC043_RS08060 (SC043_08060) rpsN 1584007..1584276 (-) 270 WP_010905608.1 30S ribosomal protein S14 -
  SC043_RS08065 (SC043_08065) - 1584379..1585062 (-) 684 WP_003131396.1 LCP family protein -
  SC043_RS08070 (SC043_08070) - 1585123..1585608 (-) 486 WP_232463608.1 LCP family protein -
  SC043_RS08075 (SC043_08075) - 1585708..1586907 (-) 1200 WP_010905605.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=824545 SC043_RS08045 WP_003131402.1 1581560..1582189(-) (vraR) [Lactococcus lactis strain B26]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=824545 SC043_RS08045 WP_003131402.1 1581560..1582189(-) (vraR) [Lactococcus lactis strain B26]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGATTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACTCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACGAGTTTTATTGATGACGAAAAAGTTTTTCCGGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATTGCATCTGCAATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGATGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416