Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R8625_RS01855 Genome accession   NZ_AP026923
Coordinates   354307..354939 (+) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 349307..359939
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS01830 (PC0054_03540) mvaD 349584..350537 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  R8625_RS01835 (PC0054_03550) - 350524..351531 (+) 1008 WP_317649271.1 phosphomevalonate kinase -
  R8625_RS01840 (PC0054_03560) fni 351515..352525 (+) 1011 WP_000210629.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R8625_RS01845 (PC0054_03570) liaF 352603..353301 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  R8625_RS01850 (PC0054_03580) - 353298..354293 (+) 996 WP_000743679.1 sensor histidine kinase -
  R8625_RS01855 (PC0054_03590) vraR 354307..354939 (+) 633 WP_000698432.1 response regulator transcription factor Regulator
  R8625_RS01860 - 355015..355698 (+) 684 Protein_365 DNA alkylation repair protein -
  R8625_RS01865 (PC0054_03610) - 355868..356107 (+) 240 WP_000754501.1 hypothetical protein -
  R8625_RS01870 (PC0054_03620) cbpG 356188..357009 (+) 822 WP_055348084.1 choline-binding protein CbpG -
  R8625_RS01875 (PC0054_03630) cbpF 357028..358050 (+) 1023 Protein_368 choline-binding protein CbpF -
  R8625_RS01880 (PC0054_03650) - 358178..359449 (-) 1272 Protein_369 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=82401 R8625_RS01855 WP_000698432.1 354307..354939(+) (vraR) [Streptococcus pneumoniae strain PZ900700054]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=82401 R8625_RS01855 WP_000698432.1 354307..354939(+) (vraR) [Streptococcus pneumoniae strain PZ900700054]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTTAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTCGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment