Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   R6I04_RS12080 Genome accession   NZ_CP137714
Coordinates   2550772..2553048 (+) Length   758 a.a.
NCBI ID   WP_003090432.1    Uniprot ID   A0A0H2ZAW8
Organism   Pseudomonas aeruginosa isolate FELIX_MS457     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 2545772..2558048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6I04_RS12060 - 2545965..2548190 (-) 2226 WP_003113369.1 NADP-dependent isocitrate dehydrogenase -
  R6I04_RS12065 icd 2548549..2549805 (+) 1257 WP_003090436.1 NADP-dependent isocitrate dehydrogenase -
  R6I04_RS12070 cspD 2549878..2550150 (-) 273 WP_003090435.1 cold shock domain-containing protein CspD -
  R6I04_RS12075 clpS 2550376..2550744 (+) 369 WP_003097649.1 ATP-dependent Clp protease adapter ClpS -
  R6I04_RS12080 clpC 2550772..2553048 (+) 2277 WP_003090432.1 ATP-dependent Clp protease ATP-binding subunit ClpA Regulator
  R6I04_RS12085 infA 2553130..2553348 (-) 219 WP_002553999.1 translation initiation factor IF-1 -
  R6I04_RS12090 - 2553453..2554160 (-) 708 WP_003108766.1 arginyltransferase -
  R6I04_RS12095 aat 2554215..2554895 (-) 681 WP_003113368.1 leucyl/phenylalanyl-tRNA--protein transferase -
  R6I04_RS12100 trxB 2554933..2555883 (-) 951 WP_003097640.1 thioredoxin-disulfide reductase -

Sequence

Protein


Download         Length: 758 a.a.        Molecular weight: 84010.68 Da        Isoelectric Point: 5.8904

>NTDB_id=823568 R6I04_RS12080 WP_003090432.1 2550772..2553048(+) (clpC) [Pseudomonas aeruginosa isolate FELIX_MS457]
MLNRELEVTLNLAFKEARAKRHEFMTVEHLLLALLDNEAAATVLRACGANLDKLRRDLQEFIDSTTPLIPQHDDERETQP
TLGFQRVLQRAVFHVQSSGKREVTGANVLVAIFSEQESQAVFLLKQQSIARIDVVNYIAHGISKVPGHAEHPQDGEQDMQ
DEEGGESATSNHPLDAYASNLNELARQGRIDPLVGREHEVERVAQILARRRKNNPLLVGEAGVGKTAIAEGLAKRIVDGQ
VPDLLADSVVYSLDLGALLAGTKYRGDFEKRFKALLNELRKRPHAVLFIDEIHTIIGAGAASGGVMDASNLLKPVLSSGE
IRCIGSTTFQEFRGIFEKDRALARRFQKVDVTEPSVEDTYGILKGLKGRFEQHHHIEYSDEALRAAAELAARYINDRHMP
DKAIDVIDEAGAYQRLQPEEKRVKRIEVAQVEDIVAKIARIPPKHVTTSDKELLRNLERDLKLTVFGQDDAIESLSTAIK
LSRAGLKAPDKPVGSFLFAGPTGVGKTEVARQLAKALGVELVRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTEAITK
TPHCVLLLDEIEKAHPEVFNLLLQVMDHGTLTDNNGRKADFRNIILIMTTNAGAEVAARASIGFNQQDHTTDAMEVIKKS
FTPEFRNRLDTIIQFGRLSTETIKSVVDKFLTELQAQLEDKRVQLEVSDAARGWLAEKGYDVQMGARPMARLIQDKIKRP
LAEEILFGELAEHGGLVHVDLKGDELAFEFEITAAEPA

Nucleotide


Download         Length: 2277 bp        

>NTDB_id=823568 R6I04_RS12080 WP_003090432.1 2550772..2553048(+) (clpC) [Pseudomonas aeruginosa isolate FELIX_MS457]
ATGTTGAATCGAGAGCTCGAAGTCACCCTCAATCTCGCCTTCAAGGAGGCGAGGGCCAAACGCCATGAATTCATGACGGT
TGAGCACCTGCTGCTGGCCTTGCTGGACAATGAGGCGGCGGCAACGGTATTGCGTGCGTGCGGTGCCAACCTGGACAAGC
TGCGGCGCGACCTGCAGGAATTCATCGATTCCACCACGCCGCTGATCCCGCAGCACGACGACGAGCGCGAAACCCAGCCG
ACGCTGGGCTTCCAGCGCGTCCTGCAGCGTGCGGTGTTCCACGTGCAGAGTTCCGGCAAGCGCGAAGTGACCGGGGCCAA
TGTCCTGGTGGCGATCTTCAGCGAACAGGAAAGCCAGGCGGTGTTCCTGCTCAAGCAGCAGAGCATCGCGCGTATCGATG
TGGTGAACTACATCGCCCATGGTATCTCCAAGGTGCCCGGGCATGCCGAACATCCGCAGGATGGGGAGCAGGATATGCAG
GATGAGGAAGGTGGCGAGTCGGCCACGTCCAACCATCCGCTGGACGCCTATGCCAGCAACCTCAACGAACTGGCTCGCCA
GGGGCGGATCGACCCGCTGGTGGGGCGTGAGCATGAAGTCGAGCGGGTGGCGCAGATCCTTGCCCGCCGGCGCAAGAACA
ACCCGCTGCTGGTAGGCGAGGCGGGGGTCGGCAAGACGGCCATCGCCGAGGGCCTGGCCAAACGCATCGTCGATGGCCAG
GTGCCGGACCTGCTGGCCGACAGCGTGGTCTACTCCCTCGACCTGGGTGCCTTGCTCGCGGGTACCAAGTACCGCGGCGA
CTTCGAGAAGCGCTTCAAGGCCTTGCTCAACGAGTTGCGCAAGCGCCCGCACGCGGTGCTGTTCATCGACGAGATCCATA
CCATCATCGGCGCCGGTGCGGCATCCGGCGGGGTAATGGACGCCTCCAACCTGCTCAAGCCGGTTCTGTCCTCGGGCGAG
ATCCGCTGCATCGGCTCGACCACCTTCCAGGAGTTCCGCGGCATCTTCGAGAAGGACCGGGCCTTGGCGCGGCGCTTCCA
GAAGGTCGACGTGACCGAGCCGTCGGTGGAAGACACCTATGGCATCCTCAAGGGCCTCAAGGGGCGCTTCGAGCAGCATC
ACCACATCGAGTACAGCGACGAGGCGCTGCGCGCCGCGGCCGAGCTGGCGGCGCGCTACATCAACGACCGGCACATGCCG
GACAAGGCCATCGACGTCATCGACGAGGCGGGCGCCTACCAGCGCCTGCAGCCGGAAGAGAAGCGCGTGAAGCGCATCGA
GGTGGCGCAGGTCGAGGATATCGTGGCGAAGATCGCGCGGATCCCGCCGAAACACGTCACCACCTCCGACAAGGAGTTGC
TGCGCAACCTCGAACGCGACCTCAAGCTGACCGTGTTCGGCCAGGACGACGCCATCGAGTCGCTGTCCACCGCGATCAAG
CTGTCCCGGGCCGGGCTAAAGGCGCCGGACAAGCCGGTCGGCTCGTTCCTCTTCGCCGGTCCCACCGGCGTGGGCAAGAC
CGAGGTGGCGCGGCAGTTGGCGAAGGCCTTGGGCGTGGAGCTGGTGCGCTTCGACATGTCCGAGTACATGGAGCGGCATA
CCGTGTCGCGGCTGATCGGTGCGCCTCCGGGCTACGTCGGCTTCGACCAGGGCGGCCTGCTCACCGAGGCGATCACCAAG
ACCCCGCACTGCGTGTTGCTGCTCGACGAGATCGAGAAGGCTCACCCGGAGGTCTTCAACCTGCTGCTGCAGGTGATGGA
CCACGGCACCCTGACCGACAACAACGGGCGCAAGGCGGACTTCCGCAACATCATCCTGATCATGACCACCAACGCCGGCG
CGGAAGTGGCGGCGCGCGCGTCGATCGGCTTCAACCAGCAGGATCACACCACCGATGCGATGGAAGTGATCAAGAAGAGC
TTCACCCCGGAGTTCCGCAACCGCCTGGATACCATCATCCAGTTCGGCCGCCTGAGCACCGAGACGATCAAGAGCGTGGT
CGACAAGTTCCTCACCGAGCTGCAGGCGCAGCTGGAGGACAAGCGCGTCCAGCTCGAGGTCAGCGATGCGGCGCGCGGCT
GGCTGGCGGAGAAGGGCTACGACGTGCAGATGGGGGCGCGACCGATGGCGCGGCTTATCCAGGACAAGATCAAGCGGCCG
TTGGCCGAGGAGATCCTGTTCGGCGAGCTGGCCGAGCATGGCGGCCTGGTGCATGTCGACCTGAAGGGCGACGAGCTGGC
CTTCGAGTTCGAGATCACGGCGGCGGAGCCCGCCTGA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(216-328)

AAA lid domain (AAA_lid_9)

(355-458)

AAA domain (Cdc48 subfamily) (AAA_2)

(491-652)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(13-62)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-739)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZAW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

38.956

100

0.423
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.667

96.57

0.402
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

37.247

100

0.389
  clpC Streptococcus mutans UA159

45.484

81.794

0.372
  clpC Lactococcus lactis subsp. cremoris KW2

44.586

82.85

0.369